Bohm C, Greitz T, Seitz R, Eriksson L
Department of Physics, University of Stockholm, Sweden.
J Cereb Blood Flow Metab. 1991 Mar;11(2):A64-8. doi: 10.1038/jcbfm.1991.39.
The computerized individually adjustable brain atlas (CBA) has been further developed. The atlas was primarily designed for anatomical localization and quantitative evaluation of data in positron emission tomography (PET), but may also be employed for other neuroimaging modalities, such as transmission computed tomography (CT) and magnetic resonance imaging (MRI). The atlas is based on anatomical information obtained from digitized cryosectioned brains. Using spatially standardized and then averaged MRI images, we demonstrate the high localization accuracy and precision of the brain atlas. This is a prerequisite for obtaining accuracy when using the atlas in the localization and the quantitative evaluation of PET data. The specification and the selection of region of interests (ROIs) by the CBA are presented and discussed.
计算机化的个体可调节脑图谱（CBA）已得到进一步发展。该图谱主要设计用于正电子发射断层扫描（PET）数据的解剖定位和定量评估，但也可用于其他神经成像模态，如透射计算机断层扫描（CT）和磁共振成像（MRI）。该图谱基于从数字化冷冻切片大脑获得的解剖信息。通过使用空间标准化然后平均的MRI图像，我们证明了脑图谱具有高定位准确性和精确性。这是在使用该图谱进行PET数据的定位和定量评估时获得准确性的先决条件。本文介绍并讨论了CBA对感兴趣区域（ROI）的规范和选择。
