Jolly M, Molta C, Hoffman G
Cleveland Clinic Foundation, Ohio, USA.
J Rheumatol. 2000 Oct;27(10):2511-2.
Wegener's granulomatosis (WG) is a systemic, granulomatous vasculitis that typically affects the upper airways, lungs, and, in most cases, the kidneys. Lung involvement occurs in 85% of patients. A classic feature of WG is multiple pulmonary nodules, which frequently cavitate. Hilar adenopathy or mediastinal masses are rare. These atypical pulmonary findings should raise suspicion of diseases other than WG and lead to biopsy with cultures, even when the diagnosis of WG appears to be certain. These guidelines proved to be reliable in a patient with WG in whom a hilar mass was associated with tuberculosis.
韦格纳肉芽肿（WG）是一种全身性肉芽肿性血管炎，通常累及上呼吸道、肺部，大多数情况下还累及肾脏。85%的患者会出现肺部受累。WG的一个典型特征是多发性肺结节，这些结节常发生空洞形成。肺门淋巴结肿大或纵隔肿块较为罕见。这些非典型肺部表现应引起对WG以外疾病的怀疑，并导致进行活检及培养，即使WG的诊断看似确定。在一名伴有肺门肿块且合并肺结核的WG患者中，这些指南被证明是可靠的。
