Hogan C M
University of Michigan, Ann Arbor.
Oncol Nurs Forum. 1991 Jan-Feb;18(1 Suppl):19-23.
Cancer treatment with biological response modifier (BRM) therapies is characterized by many of the same issues observed with other modalities. Yet, the nurse caring for the patient receiving BRM therapy frequently is faced with the need to develop interventions that respect both the integrity of investigational studies and the patient's unique needs. Coping with BRM therapy is influenced by many factors. Several models may be used simultaneously to assess coping behaviors and to provide effective interventions. The goals of investigational therapy and the management of symptom distress influence the ability to cope with BRM therapy. The interruption or impediment of normal adult developmental activities also influences the individual's response to the psychological stressors associated with this cancer therapy. Consequently, the most significant challenge faced by anyone receiving cancer therapy is the same for the individual receiving BRM therapy--living with uncertainty.
使用生物反应调节剂（BRM）疗法进行癌症治疗具有许多与其他治疗方式相同的问题。然而，护理接受BRM疗法患者的护士经常面临这样的需求，即制定既尊重研究性研究的完整性又尊重患者独特需求的干预措施。应对BRM疗法受到多种因素的影响。可以同时使用几种模型来评估应对行为并提供有效的干预措施。研究性治疗的目标和症状困扰的管理会影响应对BRM疗法的能力。正常成人发育活动的中断或阻碍也会影响个体对与这种癌症治疗相关的心理压力源的反应。因此，接受癌症治疗的任何人面临的最重大挑战对于接受BRM疗法的个体来说是相同的——在不确定性中生活。
