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脂质双层与微加工硅的核壳导体。

Core-coat conductor of lipid bilayer and micromachined silicon.

作者信息

Fromherz P, Klingler J

机构信息

Abteilung Biophysik der Universität Ulm, F.R.G.

出版信息

Biochim Biophys Acta. 1991 Feb 11;1062(1):103-7. doi: 10.1016/0005-2736(91)90340-e.

Abstract

We have etched a groove into a (110) plane of silicon and have covered it with a bilayer of glycerol monooleate. We have varied the depth of the groove, the concentration of salt in the electrolyte and the density of gramicidin in the membrane. We have clamped one end of the groove at a constant voltage with respect to the bath keeping the other end sealed or electrically open with respect to the bath. We have measured (i) the voltage at the center of the groove and at the sealed distal end and (ii) the current through the system in sealed and open configuration. We have found that the spread of voltage is in quantitative agreement with the stationary solutions of Kelvin's equation for a homogeneous cable.

摘要

我们在硅的(110)平面上蚀刻了一条凹槽,并用甘油单油酸酯双层覆盖其上。我们改变了凹槽的深度、电解质中盐的浓度以及膜中短杆菌肽的密度。我们将凹槽的一端相对于浴槽保持在恒定电压下,另一端相对于浴槽保持密封或电开放。我们测量了(i)凹槽中心和密封远端的电压,以及(ii)密封和开放配置下通过系统的电流。我们发现电压的分布与均匀电缆的开尔文方程的稳态解在数量上一致。

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