Johnston G W, Spencer E F, Wilkinson A J, Kennedy T L
Royal Victoria Hospital, Belfast.
Br J Surg. 1991 Jan;78(1):20-3. doi: 10.1002/bjs.1800780107.
From August 1969 to December 1989, 600 patients had elective proximal gastric vagotomy for duodenal ulceration with an operative mortality of 0.2 per cent. Of these, 372 patients had surgery over 10 years ago. Three hundred and forty-two patients survived for more than 10 years and, in a prospective study, 305 were reviewed, forming the basis of this 10-20-year follow-up report. Forty-six (15 per cent) have had recurrent ulceration; 80 per cent of these developed symptoms within 5 years and no patient has had recurrence after 13 years. Although 29 patients required reoperation for recurrent ulceration, the current patient satisfaction rate for Visick grades I and II is 92 per cent. Only two patients required reoperation because of gastric stasis. It is concluded that proximal gastric vagotomy is a safe and satisfactory first choice operation for duodenal ulceration.
从1969年8月至1989年12月，600例患者因十二指肠溃疡接受了选择性近端胃迷走神经切断术，手术死亡率为0.2%。其中，372例患者在10多年前接受了手术。342例患者存活超过10年，在一项前瞻性研究中，对305例患者进行了复查，形成了这份10至20年随访报告的基础。46例（15%）出现复发性溃疡；其中80%在5年内出现症状，13年后无患者复发。虽然29例患者因复发性溃疡需要再次手术，但目前Visick I级和II级患者的满意度为92%。只有2例患者因胃潴留需要再次手术。结论是，近端胃迷走神经切断术是十二指肠溃疡安全且令人满意的首选手术。
