Oulis C J, Berdouses E D
Dept. of Paediatric Dentistry, Dental School, University of Athens, Greece. Email:
Eur Arch Paediatr Dent. 2009 Dec;10(4):211-7. doi: 10.1007/BF03262684.
This was to evaluate the retention of fissure sealants (FS) and their effectiveness after resealing on caries reduction applied to first permanent molars, in a sample of children stratified according to their caries risk status in a private practice setting.
The sample was 1,274 FS applied on first permanent molars (FPM) of 380 children (6 to 8 years old). Follow-up and monitoring for resealing was 3 years after FS placement, having at least one recall visit per year. Caries risk was based on baseline dmft index: low (dmft=0), moderate (dmft=1-4), high (dmft >4), with almost half of the teeth belonging to the high-risk group. All sealed teeth were evaluated and recorded for FS failure and resealing in case of partial/total loss, as well as caries development. Survival analysis using the Cox Proportional Hazards regression model was used for data evaluation.
Of the 1,274 sealed surfaces, 927 (72.8%) needed no intervention 185 (14.5%) needed only resealing and 162 (12.7%) developed caries during the study. Of 162 carious surfaces, 107/ 675 (15.9%) were from the high caries risk children, compared with 17/144 (11.8%) and 38/455 (8.3%) from the moderate and low caries risk group respectively. The highest number of failures, 4.9% and resealing were found at first recall, declining to 1.4% at the end of the study. Development of caries followed a steady rate of 6-8% per year. Cox proportional hazards model indicated, regardless if resealing or caries development was considered a failure or resealing was a success and caries development a failure, only the high dmft index appeared in both cases to significantly increase the chance (158% and 173% respectively) of FS failure and caries development compared with moderate and low dmft index. Other variables when inserted into the hazard model, such as age, sex and number of visits, either did not show a significant effect or only marginally affected FS retention, without modifying the association between caries risk and sealant failure.
Children of a high baseline caries risk status showed lower FS retention rates and higher occlusal caries prevalence following FS loss compared with those of moderate and low risk status. Resealing does not seem to dramatically change the final outcome of the higher risk group to develop more caries, necessitating other more effective measures to increase the retention of FS on these highly vulnerable areas.
在一家私人诊所环境中,对根据龋病风险状况分层的儿童样本,评估第一恒磨牙窝沟封闭剂(FS)的保留情况及其重新封闭后在减少龋齿方面的效果。
样本为应用于380名儿童(6至8岁)第一恒磨牙(FPM)上的1274颗窝沟封闭剂。在放置窝沟封闭剂后3年进行随访和重新封闭监测,每年至少进行一次复诊。龋病风险基于基线dmft指数:低(dmft = 0)、中(dmft = 1 - 4)、高(dmft > 4),几乎一半的牙齿属于高风险组。对所有封闭的牙齿进行评估并记录窝沟封闭剂失败情况,以及在部分/全部丧失时的重新封闭情况和龋齿发展情况。使用Cox比例风险回归模型进行生存分析以评估数据。
在1274个封闭表面中,927个(72.8%)无需干预,185个(14.5%)仅需重新封闭,162个(12.7%)在研究期间发生龋齿。在162个龋损表面中,107/675(15.9%)来自高龋风险儿童,相比之下,中龋风险组为17/144(11.8%),低龋风险组为38/455(8.3%)。失败和重新封闭的最高发生率在首次复诊时为4.9%,在研究结束时降至1.4%。龋齿发展以每年6 - 8%的稳定速率进行。Cox比例风险模型表明,无论将重新封闭或龋齿发展视为失败,还是将重新封闭视为成功而龋齿发展视为失败,在这两种情况下,与中低dmft指数相比,只有高dmft指数显著增加了窝沟封闭剂失败(分别为158%和173%)和龋齿发展的几率。当将其他变量(如年龄、性别和复诊次数)纳入风险模型时,要么未显示出显著影响,要么仅对窝沟封闭剂的保留有轻微影响,而未改变龋病风险与封闭剂失败之间的关联。
与中低风险状况的儿童相比,基线龋病风险高的儿童在窝沟封闭剂丧失后显示出较低的窝沟封闭剂保留率和较高的咬合面龋齿患病率。重新封闭似乎并未显著改变高风险组发生更多龋齿的最终结果,因此需要采取其他更有效的措施来提高这些高度易感区域窝沟封闭剂的保留率。