中心性浆液性脉络膜视网膜病变患者的青光眼发病率：病例对照研究。

Frequency of glaucoma in central serous chorioretinopathy: a case-control study.

机构信息

Vitreous-Retina-Macula Consultants of New York, New York, NY 10022, USA.

出版信息

Retina. 2010 Feb;30(2):267-70. doi: 10.1097/IAE.0b013e3181c2e0f4.

DOI:10.1097/IAE.0b013e3181c2e0f4

PMID:19996820

Abstract

PURPOSE

The purpose of this study was to investigate the frequency of glaucoma and related conditions in patients with central serous chorioretinopathy (CSC), a condition associated with increased choroidal thickness.

METHODS

A case-control study was conducted. Consecutive patients with CSC examined from January 1, 2006, through July 31, 2008, were compared with a sex- and age-matched control group from the same referral practice seen during the same period for the frequency of glaucoma and related conditions. The charts of the cases and the control subjects were reviewed for diagnosis of glaucoma.

RESULTS

In 287 patients with CSC, the mean age was 56.8 years and 207 (72.1%) were men. In the control group of 235, the mean age was 59.5 years and 168 (71.5%) were men. Glaucoma was found in 10 of 287 patients (3.4%) with CSC and in 20 of 235 control subjects (8.5%, P = 0.014, odds ratio = 0.39, 95% confidence interval = 0.16-0.89). The mean intraocular pressures were similar in the two groups. However, the number of patients diagnosed with ocular hypertension (0.3% versus 3.4%, P = 0.0076) and the number of patients using pressure-lowering eye drops (3.8% versus 13.2%, P <or= 0.0001) were significantly less in the CSC group than in the control group.

CONCLUSION

Glaucoma and related conditions are less frequent in the CSC group than in the control group. In patients with CSC, increased blood supply to the optic nerve from the choroid may be a contributing factor, but there may be differences in the variances in intraocular pressure that cannot be ruled out.

摘要

目的

本研究旨在探讨与脉络膜增厚相关的中心性浆液性脉络膜视网膜病变（CSC）患者中青光眼及相关疾病的发生频率。

方法

进行了一项病例对照研究。选择 2006 年 1 月 1 日至 2008 年 7 月 31 日期间因 CSC 而就诊的连续患者，并与同期在同一转诊机构就诊的性别和年龄匹配的对照组进行比较，以评估青光眼及相关疾病的发生频率。对病例和对照患者的图表进行审查以诊断青光眼。

结果

在 287 例 CSC 患者中，平均年龄为 56.8 岁，207 例（72.1%）为男性。在 235 例对照组中，平均年龄为 59.5 岁，168 例（71.5%）为男性。CSC 患者中有 10 例（3.4%）发现青光眼，对照组中有 20 例（8.5%）（P=0.014，优势比=0.39，95%置信区间=0.16-0.89）。两组患者的平均眼压相似。然而，CSC 组中诊断为高眼压的患者（0.3%对 3.4%，P=0.0076）和使用降压眼药水的患者（3.8%对 13.2%，P<或=0.0001）明显少于对照组。