Mendelson Y, McGinn M J
Department of Biomedical Engineering, Worcester Polytechnic Institute, MA 01609.
J Clin Monit. 1991 Jan;7(1):7-12. doi: 10.1007/BF01617892.
This study describes the results from a series of human experiments demonstrating the ability to measure arterial hemoglobin oxygen saturation (SaO2) from the forearm and calf using a reflectance pulse oximeter sensor. A special optical reflectance sensor that includes a heating element was interfaced to a temperature controller and a commercial Data-scope ACCUSAT pulse oximeter that was adapted for this study to perform as a reflectance pulse oximeter. The reflectance pulse oximeter sensor was evaluated in a group of 10 healthy adult volunteers during steady-state hypoxia. Hypoxia was induced by gradually lowering the inspired fraction of oxygen in the breathing gas mixture from 100 to 12%. Simultaneous SaO2 measurements obtained from the forearm and calf with two identical reflectance pulse oximeters were compared with SaO2 values measured by a finger sensor that was interfaced to a standard Datascope ACCUSAT transmittance pulse oximeter. The equations for the best-fitted linear regression lines between the percent reflectance, SpO2(r), and transmittance, SpO2(t), values in the range between 73 and 100% were SpO2(r) = -7.06 + 1.09 SpO2(t) for the forearm (n = 91, r = 0.95) and SpO2(r) = 7.78 + 0.93 SpO2(t) for the calf (n = 93, r = 0.88). The regression analysis of the forearm data revealed a mean +/- SD error of 2.47 +/- 1.66% (SaO2 = 90-100%), 2.35 +/- 2.45% (SaO2 = 80-89%), and 2.42 +/- 1.20% (SaO2 = 70-79%). The corresponding regression analysis of the calf data revealed a mean +/- SD error of 3.36 +/- 3.06% (SaO2 = 90-100%), 3.45 +/- 4.12% (SaO2 = 80-89%), and 2.97 +/- 2.75% (SaO2 = 70-79%).(ABSTRACT TRUNCATED AT 250 WORDS)
本研究描述了一系列人体实验的结果，这些实验证明了使用反射式脉搏血氧饱和度传感器从前臂和小腿测量动脉血红蛋白氧饱和度（SaO2）的能力。一种包含加热元件的特殊光学反射传感器与温度控制器以及为本研究改装以用作反射式脉搏血氧饱和度仪的商用Data-scope ACCUSAT脉搏血氧饱和度仪相连。在一组10名健康成年志愿者处于稳态低氧期间，对反射式脉搏血氧饱和度传感器进行了评估。通过逐渐将呼吸气体混合物中的吸氧分数从100%降至12%来诱发低氧。将使用两个相同的反射式脉搏血氧饱和度仪从前臂和小腿获得的同步SaO2测量值与通过连接到标准Datascope ACCUSAT透射式脉搏血氧饱和度仪的手指传感器测量的SaO2值进行比较。在73%至100%范围内，前臂反射率百分比SpO2(r)与透射率SpO2(t)之间最佳拟合线性回归线的方程为SpO2(r)= -7.06 + 1.09 SpO2(t)（n = 91，r = 0.95），小腿的方程为SpO2(r)= 7.78 + 0.93 SpO2(t)（n = 93，r = 0.88）。前臂数据的回归分析显示，在SaO2 = 90 - 100%时，平均±标准差误差为2.47±1.66%；在SaO2 = 80 - 89%时，为2.35±2.45%；在SaO2 = 70 - 79%时，为2.42±1.２0%。小腿数据的相应回归分析显示，在SaO2 = 90 - 100%时，平均±标准差误差为3.36±3.06%；在SaO2 = 80 - 89%时，为3.45±4.12%；在SaO2 = 70 - 79%时，为2.97±2.75%。（摘要截断于250字）
