使用β-磷酸三钙牙槽窝植骨进行牙槽嵴保存的临床评估
Clinical evaluation alveolar ridge preservation with a beta-tricalcium phosphate socket graft.
作者信息
Horowitz Robert A, Mazor Ziv, Miller Robert J, Krauser Jack, Prasad Hari S, Rohrer Michael D
机构信息
Ashman Department of Periodontology, New York University College of Dentistry, New York, NY, USA.
出版信息
Compend Contin Educ Dent. 2009 Nov-Dec;30(9):588-90, 592, 594 passim; quiz 604, 606.
PURPOSE
To determine the efficacy of an alloplastic graft material, consisting of a pure-phase beta-tricalcium phosphate (beta-TCP), in the preservation of ridge volume after tooth extraction and before dental implant placement. Histomorphometric analysis was completed on a few samples to determine the percentage of vital bone over a fixed healing period.
MATERIALS AND METHODS
Patients requiring tooth extraction and bone regeneration before implant placement were included in this study. Measurements of alveolar width were made at the time of extraction and the time of implant placement. The extraction sites were grafted with a pure-phase beta-TCP and covered with a barrier. Approximately 6 months after surgery, the sites were reentered for implant placement. Cores were taken of the regenerated material for histologic analysis, with a trephine used as the first bur in preparation for some of the osteotomies. Implants were placed according to the manufacturers' recommendations and loaded at the appropriate time.
RESULTS
The beta-TCP placed at the time of grafting extraction sockets was well tolerated in all sites with all of the barriers used. There were no incidences of postoperative infection or graft rejection. At the time of implant placement, much of the graft material had resorbed and been converted to vital alveolar bone. The implant recipient sites were dense and supported placement of endosseous dental implants that were fully stable. The width of the extraction sockets was preserved to 91% of the preoperative width.
CONCLUSIONS
Extraction socket grafting with the pure-phase beta-TCP tested in this study and covered with either a resorbable collagen or dense polytetrafluoroethylene barrier is a predictable method for preserving alveolar dimensions. The graft material resorbs to a high percentage in the timeframe desired between extraction and dental implant placement, as shown clinically, radiographically, and histologically. In addition, the regenerated material in the socket has enough density to support implant placement with subsequent loading in the 4- to 6-month period used in this study.
目的
确定一种由纯相β-磷酸三钙(β-TCP)组成的异体移植材料在拔牙后和种植牙植入前保存牙槽嵴体积的疗效。对一些样本进行了组织形态计量分析,以确定在固定愈合期内活骨的百分比。
材料与方法
本研究纳入了在种植牙植入前需要拔牙和骨再生的患者。在拔牙时和种植牙植入时测量牙槽宽度。拔牙部位用纯相β-TCP移植并覆盖屏障。术后约6个月,再次切开这些部位进行种植牙植入。取再生材料的芯进行组织学分析,在准备一些截骨术时,使用环钻作为第一个钻头。根据制造商的建议植入种植体,并在适当时间加载。
结果
在所有使用的屏障的所有部位,移植拔牙窝时放置的β-TCP耐受性良好。没有术后感染或移植排斥反应的发生。在种植牙植入时,大部分移植材料已吸收并转化为活的牙槽骨。种植牙植入部位致密,支持完全稳定的骨内种植牙的植入。拔牙窝的宽度保留至术前宽度的91%。
结论
本研究中测试的用纯相β-TCP移植拔牙窝并覆盖可吸收胶原蛋白或致密聚四氟乙烯屏障是一种可预测的保存牙槽尺寸的方法。如临床、影像学和组织学所示,移植材料在拔牙和种植牙植入之间所需的时间范围内有很高比例的吸收。此外,牙槽窝内的再生材料有足够的密度来支持种植体植入,并在本研究使用的4至6个月期间进行后续加载。