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择期结直肠手术后的快速术后管理:一项对照试验。

Fast track postoperative management after elective colorectal surgery: a controlled trail.

作者信息

Feo Carlo V, Lanzara Serena, Sortini Davide, Ragazzi Riccardo, De Pinto Mario, Pansini Gian Carlo, Liboni Alberto

机构信息

Department of Surgery, Anesthesiology, and Radiology, University of Ferrara, Ferrara, Italy.

出版信息

Am Surg. 2009 Dec;75(12):1247-51.

Abstract

In the attempt to reduce postoperative complications and costs and improve outcomes, the concept of fast track surgery has been proposed. Improvements in anesthesia techniques and a better understanding of the pathophysiologic events occurring during and after surgery have made it possible. A group of patients undergoing colorectal resections with a fast track approach were investigated; specifically, the effects on postoperative morbidity, resumption of intestinal function, and duration of hospitalization. Fifty patients were managed according to a protocol, which included epidural analgesia, early ambulation, and oral feeding (fast track group); they were compared with 50 patients managed with a different protocol: no epidural analgesia, early ambulation, and early oral diet (control group). Primary outcome end-points reported include morbidity, time to passage of flatus and stool, and length of hospital stay. Fourteen complications occurred in the fast track group and 13 in the control group (P = not significant (NS)). Resumption of intestinal function occurred after 3 days, and length of hospital stay was 5 days in the fast track group compared with 4 and 7 days respectively in control patients (P = NS, P < 0.01). Patients undergoing elective colorectal resections can be managed safely with fast track protocols reducing hospital stay.

摘要

为了减少术后并发症、降低成本并改善治疗效果,人们提出了快速康复外科的概念。麻醉技术的进步以及对手术期间和术后发生的病理生理事件的更深入了解使得这一概念成为可能。对一组采用快速康复方法进行结直肠切除术的患者进行了研究;具体而言,研究了其对术后发病率、肠道功能恢复以及住院时间的影响。50名患者按照一项方案进行治疗,该方案包括硬膜外镇痛、早期活动和口服进食(快速康复组);将他们与50名采用不同方案治疗的患者进行比较:不进行硬膜外镇痛、早期活动和早期口服饮食(对照组)。报告的主要结局终点包括发病率、排气和排便时间以及住院时间。快速康复组发生了14例并发症,对照组发生了13例并发症(P = 无显著差异(NS))。快速康复组在术后3天肠道功能恢复,住院时间为5天,而对照组患者分别为4天和7天(P = NS,P < 0.01)。接受择期结直肠切除术的患者采用快速康复方案可以安全地进行治疗,同时缩短住院时间。

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