1st Department of Ophthalmology, Semmelweis University, Budapest, Hungary.
J Refract Surg. 2009 Dec;25(12):1053-60. doi: 10.3928/1081597X-20091117-04.
To evaluate femtosecond laser lens fragmentation and anterior capsulotomy in cataract surgery.
Anterior capsulotomy and phacofragmentation procedures performed with an intraocular femtosecond laser (LenSx Lasers Inc) were initially evaluated in ex vivo porcine eyes. These procedures were then performed in an initial series of nine patients undergoing cataract surgery. In addition to standard intraoperative assessments (including capsulotomy diameter accuracy and reproducibility), optical coherence tomography was used to evaluate human procedures.
For an intended 5-mm capsulorrhexis in porcine eyes, average achieved diameters were 5.88+/-0.73 mm using a standard manual technique and 5.02+/-0.04 mm using the femtosecond laser. Scanning electron microscopy revealed equally smooth cut edges of the capsulotomy with the femtosecond laser and manual technique. Compared to control porcine eyes, femtosecond laser phacofragmentation resulted in a 43% reduction in phacoemulsification power and a 51% decrease in phacoemulsification time. In a small series of human clinical procedures, femtosecond laser capsulotomies and phacofragmentation demonstrated similarly high levels of accuracy and effectiveness, with no operative complications.
Initial results with an intraocular femtosecond laser demonstrate higher precision of capsulorrhexis and reduced phacoemulsification power in porcine and human eyes.
评估飞秒激光在白内障手术中的晶状体粉碎和前囊切开术。
在离体猪眼上初步评估了采用眼内飞秒激光（LenSx Lasers Inc）进行的前囊切开术和 phacofragmentation 程序。然后，在 9 例接受白内障手术的初始系列患者中进行了这些程序。除了标准的术中评估（包括囊切开术直径的准确性和可重复性）外，还使用光学相干断层扫描来评估人类程序。
对于在猪眼上进行的预期 5mm 囊切开术，使用标准手动技术的平均实现直径为 5.88+/-0.73mm，而使用飞秒激光的平均直径为 5.02+/-0.04mm。扫描电子显微镜显示飞秒激光和手动技术的囊切开边缘同样光滑。与对照猪眼相比，飞秒激光 phacofragmentation 导致超声乳化能量降低 43%，超声乳化时间降低 51%。在一个小系列的人类临床程序中，飞秒激光囊切开术和 phacofragmentation 显示出类似的高精度和有效性，没有手术并发症。
眼内飞秒激光的初步结果表明，在猪眼和人眼中，囊切开术的精度更高，超声乳化能量降低。
