Semmelweis University, Budapest, Hungary.
J Refract Surg. 2011 Aug;27(8):558-63. doi: 10.3928/1081597X-20110623-03. Epub 2011 Jun 30.
To measure and compare sizing and positioning parameters of femtosecond laser capsulotomy with manual continuous curvilinear capsulorrhexis (CCC).
Femtosecond capsulotomies (Alcon-LenSx Lasers Inc) and CCC were carried out in 20 eyes of 20 patients, respectively. Intraocular lens (IOL) decentration, circularity, vertical and horizontal diameters of capsulotomies, and capsule overlap were measured with Adobe Photoshop (Adobe Systems Inc) 1 week, 1 month, and 1 year after surgery. Between-group differences of parameters and predictors of IOL decentration were determined with repeated measures analysis of variance, chi-square test, and logistic regression analyses.
Vertical diameter of CCC was statistically significantly higher in the first week and month. Significantly higher values of capsule overlap over 1 year and circularity in the first week showed more regular femtosecond capsulotomies. Horizontal IOL decentration was statistically significantly higher in the CCC group over 1 year. A significant difference was noted between the two groups in dichotomized horizontal decentration values at 0.4 mm with chi-square test after 1 week and 1 year (P=.035 and P=.016, respectively). In univariable general estimating equation models, type of capsulorrhexis (P<.01) and capsule overlap (P=.002) were significant predictors of horizontal decentration. Vertical diameter showed significant correlation to the overlap in the CCC group (1 week: r=-0.91; 1 month: r=-0.76, P<.01; 1 year: r=-0.62, P<.01), whereas no significant correlation was noted in the femtosecond group (P>.05).
More precise capsulotomy sizing and centering can be achieved with femtosecond laser. Properly sized, shaped, and centered femtosecond laser capsulotomies resulted in better overlap parameters that help maintain proper positioning of the IOL.
测量并比较飞秒激光囊膜切开术与手动连续环形撕囊术(CCC)的大小和定位参数。
对 20 例(20 只眼)患者分别行飞秒激光囊膜切开术(Alcon-LenSx 激光公司)和 CCC。术后 1 周、1 个月和 1 年,使用 Adobe Photoshop(Adobe Systems Inc.)测量人工晶状体(IOL)偏心、圆度、囊膜切开的垂直和水平直径以及囊膜重叠。采用重复测量方差分析、卡方检验和逻辑回归分析比较各组间参数差异及 IOL 偏心的预测因素。
术后第 1 周和第 1 个月,CCC 的垂直直径明显较大。术后第 1 周,囊膜重叠显著增加,且囊膜更圆,表明飞秒激光囊膜切开术更规则。术后第 1 年,水平 IOL 偏心在 CCC 组明显更高。卡方检验显示,术后第 1 周和第 1 年两组在水平偏心 0.4mm 的二分变量值之间存在显著差异(P=.035 和 P=.016)。在单变量一般估计方程模型中,囊膜切开术的类型(P<.01)和囊膜重叠(P=.002)是水平偏心的显著预测因素。CCC 组的垂直直径与重叠显著相关(第 1 周:r=-0.91;第 1 个月:r=-0.76,P<.01;第 1 年:r=-0.62,P<.01),而飞秒组无显著相关性(P>.05)。
飞秒激光可实现更精确的囊膜切开术大小和定位。大小、形状和位置合适的飞秒激光囊膜切开术可获得更好的重叠参数,有助于维持 IOL 的正确位置。