Department of Clinical Microbiology and Immunology, The Children's Memorial Health Institute, Warsaw, Poland.
Foodborne Pathog Dis. 2010 May;7(5):597-600. doi: 10.1089/fpd.2009.0407.
Campylobacter spp. is an important cause of gastroenteritis in humans throughout the world. However, sources of these infections are often difficult to identify. Therefore, this study aimed at analyzing the genetic relatedness of Campylobacter isolates from environmental and food samples as well as stool specimens of diarrheal patients obtained in a single geographic region in Poland. Only a few Campylobacter jejuni isolates (4/18, 22%) could be assigned to one cluster, whereas the majority were unrelated. In contrast, the majority of Campylobacter coli strains (25/35, 71%) belonged to three pulsed-field gel electrophoresis (PFGE) clusters containing isolates of various origins (i.e., water samples, chicken carcasses, and humans). Isolates belonging to the clusters showed also similar antibiotic resistance patterns and similar genotypes with respect to the occurrence of the virB11 and iam genes. This suggests that Campylobacter strains may circulate between humans, poultry, and recreational water sources in the rural region in central Poland.
空肠弯曲菌和结肠弯曲菌是全世界人类肠胃炎的重要致病菌。然而，这些感染源通常难以确定。因此，本研究旨在分析在波兰一个特定地理区域内，从环境和食物样本以及腹泻患者粪便标本中分离出的弯曲菌的遗传相关性。只有少数空肠弯曲菌分离株（4/18，22%）可以归为一个群，而大多数则没有关联。相比之下，大多数大肠弯曲菌菌株（25/35，71%）属于三个脉冲场凝胶电泳（PFGE）群，其中包含来自不同来源的分离株（即水样、鸡尸和人类）。属于这些群的分离株还表现出相似的抗生素耐药模式和相似的基因型，包括 virB11 和 iam 基因的存在。这表明在波兰中部农村地区，弯曲菌菌株可能在人类、家禽和娱乐用水源之间传播。
