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前列腺原发性精原细胞瘤。

Primary seminoma of the prostate.

机构信息

Department of Urology, Tokyo Medical University, Tokyo, Japan.

出版信息

Int J Urol. 2009 Dec;16(12):967-70. doi: 10.1111/j.1442-2042.2009.02403.x.

DOI:10.1111/j.1442-2042.2009.02403.x
PMID:20002841
Abstract

Abstract A 54-year-old gentleman was suspected of having sarcoma of the prostate because of his low serum prostate-specific antigen level (1.9 ng/mL) and an enlarged heterogeneous mass on computed tomography and magnetic resonance imaging scans. Pathological examination of the prostate needle biopsy indicated seminoma, which was confirmed with immunohistochemical staining. There was no evidence of disease in other areas on physical examination or on radiographic tests. Therefore, we diagnosed the case as a primary seminoma of the prostate, which was consequently treated with a total of three courses of bleomycin, etoposide and cisplatin chemotherapy. Complete response was obtained on computed tomography, magnetic resonance imaging and prostate needle re-biopsy. To our knowledge, there have only been five cases of primary seminoma of the prostate reported.

摘要

摘要 一位 54 岁的男性,由于其血清前列腺特异性抗原水平(1.9ng/ml)较低,且计算机断层扫描和磁共振成像扫描显示前列腺不均匀增大,因此被怀疑患有前列腺肉瘤。前列腺针吸活检的病理检查提示为精原细胞瘤,免疫组织化学染色进一步证实了这一诊断。体检和影像学检查均未发现其他部位有疾病的证据。因此,我们诊断该病例为原发性前列腺精原细胞瘤,并给予博来霉素、依托泊苷和顺铂化疗共 3 个疗程。计算机断层扫描、磁共振成像和前列腺针吸再活检均显示完全缓解。据我们所知,仅有 5 例原发性前列腺精原细胞瘤的报道。

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1
Primary seminoma of the prostate.前列腺原发性精原细胞瘤。
Int J Urol. 2009 Dec;16(12):967-70. doi: 10.1111/j.1442-2042.2009.02403.x.
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引用本文的文献

1
Diagnosis and treatment of primary seminoma of the prostate: A case report and review of literature.前列腺原发性精原细胞瘤的诊断与治疗:一例病例报告及文献复习
World J Clin Cases. 2023 Apr 6;11(10):2267-2275. doi: 10.12998/wjcc.v11.i10.2267.
2
Late recurrence of localized pure seminoma in prostate gland: A case report.前列腺局限性纯精原细胞瘤的晚期复发:一例报告
World J Clin Oncol. 2022 Jan 24;13(1):62-70. doi: 10.5306/wjco.v13.i1.62.
3
Radiotherapy as a Single Modality in Primary Seminoma of the Prostate.放射治疗作为前列腺原发性精原细胞瘤的单一治疗方式
Cureus. 2021 Apr 2;13(4):e14264. doi: 10.7759/cureus.14264.
4
Imaging of non-epithelial neoplasms of the prostate.前列腺非上皮性肿瘤的影像学表现。
Abdom Radiol (NY). 2020 Dec;45(12):4117-4132. doi: 10.1007/s00261-020-02774-2. Epub 2020 Sep 22.
5
Mixed extragonadal germ cell tumour of the prostate.前列腺混合性性腺外生殖细胞肿瘤
BMJ Case Rep. 2018 Jul 10;2018:bcr-2017-223603. doi: 10.1136/bcr-2017-223603.
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Primary extragonadal germ cell tumor: A case report on prostate seminoma.原发性性腺外生殖细胞肿瘤:一例前列腺精原细胞瘤病例报告。
Oncol Lett. 2015 Oct;10(4):2323-2326. doi: 10.3892/ol.2015.3592. Epub 2015 Aug 11.
7
Rare late metastasis of testis seminoma to the bladder.睾丸精原细胞瘤罕见的晚期膀胱转移。
Can Urol Assoc J. 2015 Nov-Dec;9(11-12):E823-5. doi: 10.5489/cuaj.3250. Epub 2015 Nov 4.
8
[Incidental undifferentiated carcinoma of the prostate: A case with unusual diagnosis].[前列腺偶发性未分化癌:一例诊断特殊的病例]
Urologe A. 2015 Nov;54(11):1602-5. doi: 10.1007/s00120-014-3650-x.
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Mixed extragonadal germ cell tumor arising from the prostate: a rare combination.起源于前列腺的混合性性腺外生殖细胞肿瘤:一种罕见的组合。
Asian J Androl. 2014 Jul-Aug;16(4):645-6. doi: 10.4103/1008-682X.122871.