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在接受冠状动脉旁路移植手术的患者中,超声检查显示颈动脉疾病严重程度较低。

Low prevalence of significant carotid artery disease on ultrasound in patients proceeding to coronary artery bypass surgery.

机构信息

Department of Orthopaedics, Prince of Wales Hospital, Sydney, New South Wales, Australia.

出版信息

Intern Med J. 2011 Sep;41(9):658-61. doi: 10.1111/j.1445-5994.2009.02138.x. Epub 2009 Dec 4.

Abstract

BACKGROUND

Cardiothoracic surgery is associated with an increased risk of perioperative stroke. Preoperative carotid ultrasonography can identify significant stenosis, but there is debate about the value of screening. The aims of this study were to (i) determine the prevalence of significant carotid artery disease in screened patients undergoing cardiothoracic surgery and (ii) correlate their ultrasonographic findings with perioperative strokes.

METHODS

Retrospective analysis of 166 patients (118 men, 48 women) who underwent a preoperative carotid ultrasound and coronary artery bypass graft surgery (CABG) from 2004 to 2007. Perioperative strokes were recorded and compared with ultrasonographic and clinical data. A separate cohort of 1423 patients (1064 men, 359 women) who underwent CABG over the same period was also evaluated.

RESULTS

Only 11 screened patients (6.6%) had significant (>70%) carotid artery disease and two of these underwent simultaneous carotid endarterectomy. There were five perioperative strokes in screened patients, four of which occurred in individuals with <50% disease. Compared with the non-screened cohort, ultrasound screened patients were older and more likely to have a prior stroke or transient ischaemic attack, hypertension, hypercholesterolaemia, peripheral vascular disease and/or renal impairment than non-screened patients. There was no significant difference in perioperative strokes compared with non-screened patients (3% vs 1.2% respectively, P= NS).

CONCLUSION

There is a low prevalence of significant carotid artery disease in ultrasound screened patients. The risk of perioperative strokes in screened patients is low and not significantly different from non-screened patients.

摘要

背景

心胸外科手术与围手术期卒中的风险增加有关。术前颈动脉超声可以识别出明显的狭窄,但关于筛查的价值存在争议。本研究的目的是:(i)确定接受心胸外科手术的筛查患者中显著颈动脉疾病的患病率;(ii)将其超声检查结果与围手术期卒中相关联。

方法

回顾性分析了 2004 年至 2007 年间进行术前颈动脉超声和冠状动脉旁路移植术(CABG)的 166 例患者(118 名男性,48 名女性)。记录围手术期卒中并与超声和临床数据进行比较。还评估了同期接受 CABG 的另外 1423 例患者(1064 名男性,359 名女性)的单独队列。

结果

只有 11 名筛选患者(6.6%)有显著的(>70%)颈动脉疾病,其中 2 名患者同时进行了颈动脉内膜切除术。筛选患者中有 5 例围手术期卒中,其中 4 例发生在疾病<50%的患者中。与未筛选组相比,超声筛选患者年龄较大,更有可能患有既往卒中或短暂性脑缺血发作、高血压、高胆固醇血症、外周血管疾病和/或肾功能不全。与未筛选患者相比,围手术期卒中无显著差异(分别为 3%和 1.2%,P=NS)。

结论

超声筛选患者中显著颈动脉疾病的患病率较低。筛选患者的围手术期卒中风险较低,与未筛选患者无显著差异。

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