Virology laboratory, University Hospital Pellegrin, Bordeaux, France.
Euro Surveill. 2009 Dec 10;14(49):19434.
We observed a prolonged shedding of virus 14 and 28 days after symptom onset in two patients with pandemic H1N1 influenza, who did not have immunodepression and were treated with neuraminidase inhibitor. This prolonged shedding was not associated with the emergence of resistance mutation H275Y in the viral neuraminidase gene.
我们观察到两名患有大流行性 H1N1 流感且无免疫抑制的患者在发病后 14 和 28 天仍持续排出病毒,他们接受了神经氨酸酶抑制剂治疗。这种持续排出病毒的现象与病毒神经氨酸酶基因中 H275Y 耐药突变的出现无关。