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2023 年人类腺病毒循环增加:在大型学术医疗中心调查循环基因型、上呼吸道病毒载量和住院情况。

Increased circulation of human adenovirus in 2023: an investigation of the circulating genotypes, upper respiratory viral loads, and hospital admissions in a large academic medical center.

机构信息

Department of Pathology, Division of Medical Microbiology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Department of Emergency Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

出版信息

J Clin Microbiol. 2024 Jan 17;62(1):e0123723. doi: 10.1128/jcm.01237-23. Epub 2023 Dec 19.

Abstract

The circulation of human adenoviruses (HAdV) increased in 2023. In this manuscript, we show that HAdV-B3 was predominant in 2023 in a cohort characterized by the Johns Hopkins Hospital System. We also show that HAdV-B3 was associated with an increase in viral loads in respiratory samples and provide a correlation with the clinical presentations and outcomes.

摘要

2023 年,人类腺病毒(HAdV)的传播有所增加。在本研究中,我们展示了在约翰霍普金斯医院系统特征的队列中,2023 年 HAdV-B3 占主导地位。我们还发现 HAdV-B3 与呼吸道样本中病毒载量的增加相关,并提供了与临床表现和结局的相关性。

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