Chemical Engineering Department, Indian Institute of Technology Roorkee, Roorkee 247667, India.
J Hazard Mater. 2010 Apr 15;176(1-3):1-13. doi: 10.1016/j.jhazmat.2009.11.038. Epub 2009 Nov 11.
Cyanides are fast-acting poisons, can be lethal if exposed in excess. In spite of fact, cyanides are discharged as effluents in large scale from industries every year. Certain bacteria, fungi, algae and plants produce cyanides. It has been observed that microbes and plant systems can degrade cyanides to less toxic compounds. There are many enzymes, which are produced by microorganisms that utilize cyanides as substrate to make alanine, glutamic acid, alfa-amino-butyric acid, beta-cyanoalanine, etc. Present paper deals with different enzymes, their mechanisms and corresponding pathways with respect to the known biochemistry of enzyme and feasibility for the use in treatment of cyanides containing industrial effluents.
氰化物是一种作用迅速的毒物,过量暴露则有致命危险。尽管如此,氰化物每年仍作为废水从工业企业大量排放。某些细菌、真菌、藻类和植物会产生氰化物。人们已经注意到微生物和植物系统可以将氰化物降解为毒性较低的化合物。许多微生物产生的酶可以利用氰化物作为底物生成丙氨酸、谷氨酸、α-氨基丁酸、β-氰基丙氨酸等物质。本文主要论述了不同酶的作用机制及其相应途径,涉及已知的酶生物化学特性和在处理含氰工业废水方面的应用可行性。