Lee Chen-Chiao, Wu Andrew, Garg Madhur, Mutyala Subhakar, Kalnicki Shalom, Sayed Gary, Mah Dennis
Department of Radiation Oncology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USA.
Med Dosim. 2011 Spring;36(1):1-5. doi: 10.1016/j.meddos.2009.10.001. Epub 2009 Nov 17.
Intensity-modulated radiation therapy (IMRT) has been applied for treatments of primary head with neck nodes, lung with supraclavicular nodes, and high-risk prostate cancer with pelvis wall nodes, all of which require large fields. However, the design of the Varian multileaf collimator requires fields >14 cm in width to be split into 2 or more carriage movements. With the split-field technique, both the number of monitor units (MUs) and total treatment time are significantly increased. Although many different approaches have been investigated to reduce the MU, including introducing new leaf segmentation algorithms, none have resulted in widespread success. In addition, for most clinics, writing such algorithms is not a feasible solution, particularly with commercial treatment planning systems. We introduce a new approach that can minimize the number of split fields and reduce the total MUs, thereby reducing treatment time. The technique is demonstrated on the Eclipse planning system V7.3, but could be generalized to any other system.
调强放射治疗（IMRT）已应用于治疗伴有颈部淋巴结的原发性头颈部肿瘤、伴有锁骨上淋巴结的肺癌以及伴有盆腔壁淋巴结的高危前列腺癌，所有这些都需要大野照射。然而，瓦里安多叶准直器的设计要求宽度大于14 cm的射野要分成2次或更多次机架运动。采用分野技术时，监测单位（MU）数量和总治疗时间都会显著增加。尽管已经研究了许多不同的方法来减少MU，包括引入新的叶片分割算法，但均未取得广泛成功。此外，对于大多数临床机构而言，编写此类算法并非可行的解决方案，尤其是对于商业治疗计划系统。我们引入了一种新方法，该方法可以最大限度地减少分野数量并减少总MU，从而缩短治疗时间。该技术在Eclipse计划系统V7.3上得到了验证，但也可推广应用于任何其他系统。
