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季节性流感 A(H1N1)、A(H3N2) 和 B 流感病毒的流行病学、抗原和遗传特征:世卫组织关于 2009-2010 北半球季节使用流感疫苗成分建议的基础。

Epidemiological, antigenic and genetic characteristics of seasonal influenza A(H1N1), A(H3N2) and B influenza viruses: basis for the WHO recommendation on the composition of influenza vaccines for use in the 2009-2010 northern hemisphere season.

机构信息

WHO Collaborating Centre for Reference and Research on Influenza, VIDRL, Melbourne, Australia.

出版信息

Vaccine. 2010 Feb 3;28(5):1156-67. doi: 10.1016/j.vaccine.2009.11.043. Epub 2009 Dec 9.

DOI:10.1016/j.vaccine.2009.11.043
PMID:20004635
Abstract

Influenza vaccines form an important component of the global response against infections and subsequent illness caused in man by influenza viruses. Twice a year, in February and September, the World Health Organisation through its Global Influenza Surveillance Network (GISN), recommends appropriate influenza viruses to be included in the seasonal influenza vaccine for the upcoming Northern and Southern Hemisphere winters. This recommendation is based on the latest data generated from many sources and the availability of viruses that are suitable for vaccine manufacture. This article gives a summary of the data and background to the recommendations for the 2009-2010 Northern Hemisphere influenza vaccine formulation.

摘要

流感疫苗是全球应对流感病毒感染及其引发的疾病的重要组成部分。世界卫生组织(世卫组织)通过其全球流感监测网络(GISN),每年在 2 月和 9 月两次建议将适当的流感病毒纳入北半球和南半球即将到来的冬季季节性流感疫苗。这一建议是基于从多方面获得的最新数据以及可用于疫苗生产的病毒情况。本文概述了 2009-2010 年北半球流感疫苗配方建议的相关数据和背景情况。

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