世界卫生组织关于2013 - 2014年北半球流感疫苗所用病毒的建议：2012年10月至2013年1月收集的甲型H1N1pdm09流感病毒、甲型H3N2流感病毒和乙型流感病毒的流行病学、抗原性及基因特征

WHO recommendations for the viruses used in the 2013-2014 Northern Hemisphere influenza vaccine: Epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from October 2012 to January 2013.

作者信息

Barr Ian G, Russell Colin, Besselaar Terry G, Cox Nancy J, Daniels Rod S, Donis Ruben, Engelhardt Othmar G, Grohmann Gary, Itamura Shigeyuki, Kelso Anne, McCauley John, Odagiri Takato, Schultz-Cherry Stacey, Shu Yuelong, Smith Derek, Tashiro Masato, Wang Dayan, Webby Richard, Xu Xiyan, Ye Zhiping, Zhang Wenqing

机构信息

WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory (VIDRL), Melbourne, Australia.

University of Cambridge, UK.

出版信息

Vaccine. 2014 Aug 20;32(37):4713-25. doi: 10.1016/j.vaccine.2014.02.014. Epub 2014 Feb 28.

DOI:10.1016/j.vaccine.2014.02.014

PMID:24582632

Abstract

In February the World Health Organisation (WHO) recommends influenza viruses to be included in influenza vaccines for the forthcoming winter in the Northern Hemisphere. These recommendations are based on data collected by National Influenza Centres (NICs) through the WHO Global Influenza Surveillance and Response System (GISRS) and a more detailed analysis of representative and potential antigenically variant influenza viruses from the WHO Collaborating Centres for Influenza (WHO CCs) and Essential Regulatory Laboratories (ERLs). This article provides a detailed summary of the antigenic and genetic properties of viruses and additional background data used by WHO experts during development of the recommendations of the 2013-2014 Northern Hemisphere influenza vaccine composition.

摘要

2月，世界卫生组织（WHO）建议将流感病毒纳入北半球即将到来的冬季流感疫苗。这些建议基于国家流感中心（NICs）通过WHO全球流感监测与应对系统（GISRS）收集的数据，以及对来自WHO流感合作中心（WHO CCs）和基本监管实验室（ERLs）的代表性和潜在抗原变异流感病毒进行的更详细分析。本文详细总结了病毒的抗原和基因特性，以及WHO专家在制定2013 - 2014年北半球流感疫苗成分建议过程中使用的其他背景数据。