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中国成年活体供肝者标准肝脏体积的评估

Estimation of standard liver volume in Chinese adult living donors.

作者信息

Fu-Gui L, Lu-Nan Y, Bo L, Yong Z, Tian-Fu W, Ming-Qing X, Wen-Tao W, Zhe-Yu C

机构信息

Department of General Surgery, China Hospital, Chengdu, Sichuan Province China.

出版信息

Transplant Proc. 2009 Dec;41(10):4052-6. doi: 10.1016/j.transproceed.2009.08.079.

DOI:10.1016/j.transproceed.2009.08.079
PMID:20005340
Abstract

AIM

To determine a formula predicting the standard liver volume based on body surface area (BSA) or body weight in Chinese adults.

MATERIALS AND METHODS

A total of 115 consecutive right-lobe living donors not including the middle hepatic vein underwent right hemi-hepatectomy. No organs were used from prisoners, and no subjects were prisoners. Donor anthropometric data including age, gender, body weight, and body height were recorded prospectively. The weights and volumes of the right lobe liver grafts were measured at the back table. Liver weights and volumes were calculated from the right lobe graft weight and volume obtained at the back table, divided by the proportion of the right lobe on computed tomography. By simple linear regression analysis and stepwise multiple linear regression analysis, we correlated calculated liver volume and body height, body weight, or body surface area.

RESULTS

The subjects had a mean age of 35.97 +/- 9.6 years, and a female-to-male ratio of 60:55. The mean volume of the right lobe was 727.47 +/- 136.17 mL, occupying 55.59% +/- 6.70% of the whole liver by computed tomography. The volume of the right lobe was 581.73 +/- 96.137 mL, and the estimated liver volume was 1053.08 +/- 167.56 mL. Females of the same body weight showed a slightly lower liver weight. By simple linear regression analysis and stepwise multiple linear regression analysis, a formula was derived based on body weight. All formulae except the Hong Kong formula overestimated liver volume compared to this formula.

CONCLUSIONS

The formula of standard liver volume, SLV (mL) = 11.508 x body weight (kg) + 334.024, may be applied to estimate liver volumes in Chinese adults.

摘要

目的

确定一个基于中国成年人的体表面积(BSA)或体重预测标准肝脏体积的公式。

材料与方法

连续115例不包括肝中静脉的右半肝活体供者接受了右半肝切除术。未使用来自囚犯的器官,且无受试者为囚犯。前瞻性记录供者的人体测量数据,包括年龄、性别、体重和身高。在手术后台测量右叶肝移植物的重量和体积。根据手术后台获得的右叶移植物重量和体积,除以计算机断层扫描中右叶的比例,计算肝脏重量和体积。通过简单线性回归分析和逐步多元线性回归分析,将计算出的肝脏体积与身高、体重或体表面积进行关联。

结果

受试者的平均年龄为35.97±9.6岁,男女比例为60:55。右叶的平均体积为727.47±136.17 mL,计算机断层扫描显示其占全肝的55.59%±6.70%。右叶体积为581.73±96.137 mL,估计肝脏体积为1053.08±167.56 mL。相同体重的女性肝脏重量略低。通过简单线性回归分析和逐步多元线性回归分析,得出了一个基于体重的公式。与该公式相比,除香港公式外的所有公式均高估了肝脏体积。

结论

标准肝脏体积公式SLV(mL)=11.508×体重(kg)+334.024可用于估计中国成年人的肝脏体积。

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