Chan See Ching, Liu Chi Leung, Lo Chung Mau, Lam Banny K, Lee Evelyn W, Wong Yik, Fan Sheung Tat
Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China.
World J Gastroenterol. 2006 Apr 14;12(14):2217-22. doi: 10.3748/wjg.v12.i4.2217.
To estimate the standard liver weight for assessing adequacies of graft size in live donor liver transplantation and remnant liver in major hepatectomy for cancer.
In this study, anthropometric data of body weight and body height were tested for a correlation with liver weight in 159 live liver donors who underwent donor right hepatectomy including the middle hepatic vein. Liver weights were calculated from the right lobe graft weight obtained at the back table, divided by the proportion of the right lobe on the computed tomography.
The subjects, all Chinese, had a mean age of 35.8+/-10.5 years, and a female to male ratio of 118:41. The mean volume of the right lobe was 710.14+/-131.46 mL and occupied 64.55%+/-4.47% of the whole liver on computed tomography. Right lobe weighed 598.90+/-117.39 g and the estimated liver weight was 927.54+/-168.78 g. When body weight and body height were subjected to multiple stepwise linear regression analysis, body height was found to be insignificant. Females of the same body weight had a slightly lower liver weight. A formula based on body weight and gender was derived: Estimated standard liver weight (g) = 218 + BW (kg) x 12.3 + gender x 51 (R2 = 0.48) (female = 0, male = 1). Based on the anthropometric data of these 159 subjects, liver weights were calculated using previously published formulae derived from studies on Caucasian, Japanese, Korean, and Chinese. All formulae overestimated liver weights compared to this formula. The Japanese formula overestimated the estimated standard liver weight (ESLW) for adults less than 60 kg.
A formula applicable to Chinese males and females is available. A formula for individual races appears necessary.
评估标准肝脏重量，以用于活体肝移植中评估移植物大小是否合适以及肝癌肝大部切除术后残余肝脏情况。
本研究中，对159例行含肝中静脉的右半肝供肝切除术的活体肝供者的体重和身高人体测量数据与肝脏重量的相关性进行了检测。肝脏重量通过在后台获取的右叶移植物重量除以计算机断层扫描中右叶所占比例来计算。
所有受试者均为中国人，平均年龄35.8±10.5岁，男女比例为118:41。右叶平均体积为710.14±131.46 mL，在计算机断层扫描中占全肝的64.55%±4.47%。右叶重量为598.90±117.39 g，估计肝脏重量为927.54±168.78 g。对体重和身高进行多元逐步线性回归分析时，发现身高无显著意义。相同体重的女性肝脏重量略低。得出了一个基于体重和性别的公式：估计标准肝脏重量（g）=218+体重（kg）×12.3+性别×51（R2 = 0.48）（女性=0，男性=1）。根据这159名受试者的人体测量数据，使用先前发表的源自对高加索人、日本人、韩国人和中国人研究的公式计算肝脏重量。与该公式相比，所有公式均高估了肝脏重量。日本公式高估了体重小于6 kg的成年人的估计标准肝脏重量（ESLW）。
有一个适用于中国男性和女性的公式。针对各个种族的公式似乎是必要的。
