Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Eur J Obstet Gynecol Reprod Biol. 2010 Feb;148(2):152-7. doi: 10.1016/j.ejogrb.2009.10.031. Epub 2009 Dec 14.
The objective of this study was to examine if patients with "early rupture of membranes (ROM)" after spontaneous onset of labor are at increased risk of cesarean section.
The rate of cesarean section was examined in 447 term singleton nulliparas who were admitted after the spontaneous onset of labor. The cases were divided into 2 groups: (1) "early ROM", defined as ROM at a cervical dilatation <4 cm (n=109); and (2) "late ROM", ROM at a cervical dilatation >or=4 cm (n=338).
(1) "Early ROM" occurred in 24.4% of the cases and the overall cesarean section rate was 5.6%; (2) there were no significant differences in the clinical characteristics including prepregnancy BMI, proportion of complicated pregnancies, total duration of labor, proportion of regional anesthesia, gestational age at delivery, and birthweight between the two groups of cases. However gravidas with "early ROM" were of advanced maternal age and had less cervical dilation on admission, shorter duration of 1st stage of labor, and more frequent use of oxytocin augmentation; (3) patients with "early ROM" had a threefold higher rate (11.9% vs. 3.6%) of cesarean section and a fourfold higher rate (11.9% vs. 3.0%) of cesarean section due to failure of progress than did those with "late ROM" (p<0.005 for each); (3) 92% (23/25) of cesarean sections were performed due to failure to progress; and (4) there was no significant difference in the rate of histologic chorioamnionitis between the two groups of cases.
"Early ROM" after the spontaneous onset of labor is a risk factor for cesarean section in term singleton nulliparas.
本研究旨在探讨自发性临产孕妇发生“胎膜早破(ROM)”后行剖宫产术的风险是否增加。
本研究纳入了 447 例自发性临产的足月单胎初产妇,根据入院时的宫颈扩张程度将其分为两组:(1)“早期 ROM”,定义为宫颈扩张<4cm 时发生 ROM(n=109);(2)“晚期 ROM”,定义为宫颈扩张≥4cm 时发生 ROM(n=338)。
(1)“早期 ROM”的发生率为 24.4%,总体剖宫产率为 5.6%;(2)两组患者的临床特征(包括孕前 BMI、复杂妊娠比例、总产程、椎管内麻醉比例、分娩时的孕周和出生体重)无显著差异。然而,“早期 ROM”孕妇的母亲年龄较大,入院时宫颈扩张程度较小,第一产程较短,催产素引产的使用率较高;(3)“早期 ROM”组的剖宫产率(11.9%比 3.6%)和因产程进展不良而行剖宫产的比例(11.9%比 3.0%)均显著高于“晚期 ROM”组(p<0.005);(3)92%(23/25)的剖宫产术是由于产程进展不良;(4)两组患者的组织学绒毛膜羊膜炎发生率无显著差异。
自发性临产孕妇发生“早期 ROM”是足月单胎初产妇行剖宫产术的危险因素。