Department of Neurosurgery, 7th Floor, Neurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India.
J Clin Neurosci. 2010 Jan;17(1):38-42. doi: 10.1016/j.jocn.2009.04.022. Epub 2009 Dec 14.
Ophthalmic segment aneurysms account for about 5% of all intracranial aneurysms. Anatomical complexity of the paraclinoid region makes surgical management of aneurysms arising from the ophthalmic segment challenging. This study was carried out to assess the presenting features, complications and outcomes after surgical treatment of ophthalmic segment aneurysms. The authors retrospectively analysed the clinical records of patients with ophthalmic aneurysms treated at our Institute from January 2001 to September 2008, which constituted about 9% (78/850) of all intracranial aneurysms. Of the 78 ophthalmic segment aneurysms, six patients (8%) had giant aneurysms and 19 (24%) patients had multiple aneurysms. Fifty-six patients underwent microsurgery, with direct clipping in most. The mean age was 42 years (range 12-75 years) and the mean follow-up was 8 months (range, 2-93 months). A good outcome was achieved in 46 (83%) patients (Glasgow Outcome Scale [GOS] score 4-5) and 17% had a poor outcome (GOS score 1-3) at last follow-up. The overall complication rate was 21% (12/56), most of which were transient complications, with 3.5% (2/56) mortality. Direct microsurgical clipping remains our preferred treatment approach, whenever possible, for ophthalmic segment aneurysms. This surgery has an acceptable complication rate and leads to a good outcome in more than 80% of patients with ophthalmic aneurysms. Use of modern microsurgical instrumentation and endovascular adjuncts can further reduce the surgical morbidity associated with these vascular lesions.
眼段动脉瘤约占所有颅内动脉瘤的 5%。由于眶内段解剖结构复杂,因此手术治疗该部位的动脉瘤极具挑战性。本研究旨在评估我院自 2001 年 1 月至 2008 年 9 月收治的眼段动脉瘤患者的临床表现、并发症及治疗结果。作者对我院 2001 年 1 月至 2008 年 9 月间收治的颅内动脉瘤患者的临床资料进行了回顾性分析,其中眼段动脉瘤占同期颅内动脉瘤的 9%(78/850)。78 例眼段动脉瘤中,有 6 例(8%)为巨大动脉瘤,19 例(24%)为多发动脉瘤。56 例行显微手术治疗,其中多数采用直接夹闭。患者的平均年龄为 42 岁(12-75 岁),平均随访 8 个月(2-93 个月)。末次随访时,46 例(83%)患者预后良好(格拉斯哥预后评分 4-5 分),17%预后较差(格拉斯哥预后评分 1-3 分)。总并发症发生率为 21%(12/56),大多数为一过性并发症,死亡率为 3.5%(2/56)。只要可能,我们仍首选直接显微手术夹闭治疗眼段动脉瘤,该手术方法并发症发生率可接受,超过 80%的眼段动脉瘤患者可获得良好预后。采用现代显微手术器械和血管内辅助技术可进一步降低此类血管病变相关的手术并发症。