Department of Neurobiology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Cell. 2009 Dec 11;139(6):1053-5. doi: 10.1016/j.cell.2009.11.041.
Protein tethers can bridge gaps between membranes. Ren et al. (2009) now provide evidence that the yeast Dsl1 complex tethers vesicles to the endoplasmic reticulum (ER) by binding ER SNARE proteins at its base and capturing vesicles using a loop region that extends 20 nm from the ER membrane.
蛋白质绳可以桥接膜之间的间隙。Ren 等人(2009 年)现在提供了证据,表明酵母 Dsl1 复合物通过在其基部结合 ER SNARE 蛋白,并用从 ER 膜延伸 20nm 的环区捕获囊泡,将囊泡连接到内质网 (ER)。