Division of Pediatric Infectious Diseases, University Children's Hospital Basel, P.O. Box, CH-4005, Basel, Switzerland.
Vaccine. 2009 Dec 30;27 Suppl 6:G9-G12. doi: 10.1016/j.vaccine.2009.10.010.
Impressive success has been achieved worldwide with population based immunisation programmes against several serious infectious diseases. This success is being threatened: the incidence of previously frequent, potentially devastating diseases decreases as a consequence of successful immunisation programmes and attention of the public shifts towards true and alleged "side effects" of vaccines. This can lead to the dilemma of waning public confidence in the necessity, tolerability and safety of vaccinations. Therefore, continuous evaluation of risks and benefits of vaccines is required and results of these need to be communicated broadly to strengthen the confidence in immunisation programmes.
全球范围内，基于人群的免疫规划在预防多种严重传染病方面取得了显著成效。但这种成功正面临威胁：由于免疫规划的成功实施，曾经频繁发生的、具有潜在破坏性的疾病发病率降低，而公众的注意力转向疫苗的真正和所谓的“副作用”。这可能导致公众对疫苗接种的必要性、耐受性和安全性的信心下降，从而陷入困境。因此，需要持续评估疫苗的风险和效益，并广泛传播这些结果，以增强对免疫规划的信心。
