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Roles of inositol phosphates and inositol pyrophosphates in development, cell signaling and nuclear processes.

作者信息

Tsui Marco M, York John D

机构信息

Department of Pharmacology and Cancer Biology, Howard Hughes Medical Institute, Duke University Medical Center, Box 3813, Durham, NC 27710, USA.

出版信息

Adv Enzyme Regul. 2010;50(1):324-37. doi: 10.1016/j.advenzreg.2009.12.002. Epub 2009 Dec 16.

Abstract
摘要

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Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma.
Oncogene. 2009 Jun 25;28(25):2383-92. doi: 10.1038/onc.2009.113. Epub 2009 May 11.
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OsITL1 gene encoding an inositol 1,3,4-trisphosphate 5/6-kinase is a negative regulator of osmotic stress signaling.
Biotechnol Lett. 2008 Sep;30(9):1687-92. doi: 10.1007/s10529-008-9730-5. Epub 2008 Apr 18.
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Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups.
Chem Biol. 2008 Mar;15(3):274-86. doi: 10.1016/j.chembiol.2008.01.011.
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Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis.
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IP7 guards the CDK gate.
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