由于社区获得性耐甲氧西林金黄色葡萄球菌的一种不寻常菌株，大学橄榄球队队员中爆发了皮肤感染。
Outbreak of skin infections in college football team members due to an unusual strain of community-acquired methicillin-susceptible Staphylococcus aureus.
机构信息
Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
出版信息
J Clin Microbiol. 2010 Feb;48(2):609-11. doi: 10.1128/JCM.02297-09. Epub 2009 Dec 9.
Abstract
We report a skin and soft-tissue infection outbreak among football team members due to a USA300 methicillin-susceptible Staphylococcus aureus (MRSA) strain with genes coding for Panton-Valentine leukocidin and the arginine catabolic mobile element. We postulate that the strain is a community-associated USA300 MRSA strain that lost methicillin resistance but retained important virulence factors.
摘要
我们报告了一起由携带编码杀白细胞素和精氨酸分解移动元件的 USA300 型甲氧西林敏感金黄色葡萄球菌（MRSA）菌株引起的足球队员皮肤和软组织感染爆发。我们推测该菌株是一种社区获得性 USA300 型 MRSA 菌株，它失去了耐甲氧西林的能力，但保留了重要的毒力因子。
相似文献
1
Outbreak of skin infections in college football team members due to an unusual strain of community-acquired methicillin-susceptible Staphylococcus aureus.由于社区获得性耐甲氧西林金黄色葡萄球菌的一种不寻常菌株，大学橄榄球队队员中爆发了皮肤感染。
J Clin Microbiol. 2010 Feb;48(2):609-11. doi: 10.1128/JCM.02297-09. Epub 2009 Dec 9.
2
Molecular characteristics of community-acquired methicillin-resistant Staphylococcus aureus in Hokkaido, northern main island of Japan: identification of sequence types 6 and 59 Panton-Valentine leucocidin-positive community-acquired methicillin-resistant Staphylococcus aureus.日本北海道地区社区获得性耐甲氧西林金黄色葡萄球菌的分子特征： 6 型和 59 型 Panton-Valentine 白细胞毒素阳性社区获得性耐甲氧西林金黄色葡萄球菌的鉴定。
Microb Drug Resist. 2011 Jun;17(2):241-50. doi: 10.1089/mdr.2010.0136. Epub 2011 Mar 13.
3
Increase in the prevalence of Panton-Valentine leukocidin and clonal shift in community-onset methicillin-resistant Staphylococcus aureus causing skin and soft-tissue infections in the Rhine-Neckar Region, Germany, 2012-2016.2012-2016 年德国莱茵-内卡地区社区获得性耐甲氧西林金黄色葡萄球菌引起的皮肤和软组织感染中，Panton-Valentine 白细胞毒素和克隆转移的流行率增加。
Int J Antimicrob Agents. 2019 Mar;53(3):261-267. doi: 10.1016/j.ijantimicag.2018.10.026. Epub 2018 Nov 6.
4
Epidemiology and molecular characteristics of community-associated methicillin-resistant and methicillin-susceptible Staphylococcus aureus from skin/soft tissue infections in a children's hospital in Beijing, China.中国北京一家儿童医院皮肤/软组织感染中社区相关性耐甲氧西林金黄色葡萄球菌和甲氧西林敏感金黄色葡萄球菌的流行病学和分子特征。
Diagn Microbiol Infect Dis. 2010 May;67(1):1-8. doi: 10.1016/j.diagmicrobio.2009.12.006. Epub 2010 Mar 12.
5
[Investigation of SCCmec types and Panton-Valentine leukocidin in community-acquired and nosocomial Staphylococcus aureus strains: comparing skin and soft tissue infections to the other infections].社区获得性和医院获得性金黄色葡萄球菌菌株中葡萄球菌染色体盒式甲氧西林耐药基因（SCCmec）类型及杀白细胞素的研究：皮肤和软组织感染与其他感染的比较
Mikrobiyol Bul. 2012 Jul;46(3):341-51.
6
Recurrent community-acquired methicillin-resistant Staphylococcus aureus infections in an HIV-infected person.HIV 感染者反复发生社区获得性耐甲氧西林金黄色葡萄球菌感染。
J Clin Microbiol. 2011 May;49(5):2047-53. doi: 10.1128/JCM.02423-10. Epub 2011 Mar 9.
7
Genetic diversity of pvl-positive community-onset methicillin-resistant Staphylococcus aureus isolated at a university hospital in Japan.日本某大学医院分离出的Panton-Valentine杀白细胞素阳性社区获得性耐甲氧西林金黄色葡萄球菌的遗传多样性
J Infect Chemother. 2017 Dec;23(12):856-858. doi: 10.1016/j.jiac.2017.06.002. Epub 2017 Jun 24.
8
Community-associated methicillin-resistant Staphylococcus aureus in non-outbreak skin infections.非暴发情况下皮肤感染中的社区获得性耐甲氧西林金黄色葡萄球菌
Braz J Microbiol. 2015 Mar 4;45(4):1401-7. doi: 10.1590/s1517-83822014000400034. eCollection 2014.
9
The molecular epidemiology and evolution of the Panton-Valentine leukocidin-positive, methicillin-resistant Staphylococcus aureus strain USA300 in Western Australia.西澳大利亚州泛耐药性、耐甲氧西林金黄色葡萄球菌USA300菌株的分子流行病学与进化
Clin Microbiol Infect. 2009 Aug;15(8):770-6. doi: 10.1111/j.1469-0691.2009.02792.x. Epub 2009 Jun 24.
10
Trial to control an outbreak of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus at a boarding school in Japan.日本一所寄宿学校中控制 Panton-Valentine 白细胞毒素阳性耐甲氧西林金黄色葡萄球菌爆发的试验。
Am J Infect Control. 2011 Dec;39(10):858-65. doi: 10.1016/j.ajic.2011.02.010. Epub 2011 Jun 12.
引用本文的文献
1
diversity of methicillin-resistant and -susceptible in clinical strains from Malaysia: a high prevalence of invasive European -type t032.马来西亚临床菌株中耐甲氧西林和对甲氧西林敏感的多样性：侵袭性欧洲t032型的高流行率
PeerJ. 2021 Apr 8;9:e11195. doi: 10.7717/peerj.11195. eCollection 2021.
2
Arginine Catabolic Mobile Element in Evolution and Pathogenicity of the Community-Associated Methicillin-Resistant Strain USA300.精氨酸分解代谢移动元件在社区获得性耐甲氧西林金黄色葡萄球菌USA300菌株进化及致病性中的作用
Microorganisms. 2020 Feb 18;8(2):275. doi: 10.3390/microorganisms8020275.
3
Genomic Characterization of USA300 Methicillin-Resistant Staphylococcus aureus (MRSA) to Evaluate Intraclass Transmission and Recurrence of Skin and Soft Tissue Infection (SSTI) Among High-Risk Military Trainees.对美国300型耐甲氧西林金黄色葡萄球菌（MRSA）进行基因组特征分析，以评估高危军事训练学员皮肤和软组织感染（SSTI）的类内传播及复发情况。
Clin Infect Dis. 2017 Aug 1;65(3):461-468. doi: 10.1093/cid/cix327.
4
Characterization of novel lytic phage and defining their combinatorial virulence using the OmniLog® system.新型裂解性噬菌体的特性鉴定及其使用OmniLog®系统确定其组合毒力
Bacteriophage. 2016 Aug 5;6(3):e1219440. doi: 10.1080/21597081.2016.1219440. eCollection 2016 Jul-Sep.
5
Longitudinal Assessment of Colonization With Staphylococcus aureus in Healthy Collegiate Athletes.健康大学生运动员金黄色葡萄球菌定植的纵向评估
J Pediatric Infect Dis Soc. 2016 Jun;5(2):105-13. doi: 10.1093/jpids/piu108. Epub 2014 Nov 5.
6
Effects of High-Intensity Endurance Exercise on Epidermal Barriers against Microbial Invasion.高强度耐力运动对表皮屏障抵抗微生物入侵的影响。
J Sports Sci Med. 2013 Mar 1;12(1):44-51. eCollection 2013.
7
The first case of fatal pneumonia caused by Panton-Valentine leukocidin-producing Staphylococcus aureus in an infant in the Czech Republic.捷克共和国首例婴儿由产化脓性链球菌杀白细胞素的金黄色葡萄球菌引起的致命性肺炎。
Folia Microbiol (Praha). 2013 May;58(3):225-8. doi: 10.1007/s12223-012-0200-z. Epub 2012 Oct 17.
8
A typical hospital-acquired methicillin-resistant Staphylococcus aureus clone is widespread in the community in the Gaza strip.在加沙地带，一种典型的医院获得性耐甲氧西林金黄色葡萄球菌（MRSA）克隆在社区中广泛传播。
PLoS One. 2012;7(8):e42864. doi: 10.1371/journal.pone.0042864. Epub 2012 Aug 16.
9
Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies.Panton-Valentine 白细胞毒素并非金黄色葡萄球菌皮肤感染结局的主要决定因素：来自 CANVAS 研究的评估。
PLoS One. 2012;7(5):e37212. doi: 10.1371/journal.pone.0037212. Epub 2012 May 18.
10
Prevalence and sequence variation of panton-valentine leukocidin in methicillin-resistant and methicillin-susceptible staphylococcus aureus strains in the United States.美国耐甲氧西林金黄色葡萄球菌和甲氧西林敏感金黄色葡萄球菌菌株中泛耐药性杀白细胞素的流行情况和序列变异。
J Clin Microbiol. 2012 Jan;50(1):86-90. doi: 10.1128/JCM.05564-11. Epub 2011 Nov 16.
本文引用的文献
1
contribution of genetically restricted, methicillin-susceptible strains to the ongoing epidemic of community-acquired Staphylococcus aureus infections.基因受限的甲氧西林敏感菌株对社区获得性金黄色葡萄球菌感染持续流行的作用。
Clin Infect Dis. 2009 Aug 15;49(4):536-42. doi: 10.1086/600881.
2
Clinical practice: colonization, fomites, and virulence: rethinking the pathogenesis of community-associated methicillin-resistant Staphylococcus aureus infection.临床实践：定植、污染物与毒力：重新思考社区获得性耐甲氧西林金黄色葡萄球菌感染的发病机制
Clin Infect Dis. 2008 Mar 1;46(5):752-60. doi: 10.1086/526773.
3
Increase of the USA300 clone among community-acquired methicillin-susceptible Staphylococcus aureus causing invasive infections.在美国社区获得性对甲氧西林敏感的金黄色葡萄球菌引起侵袭性感染中USA300克隆株的增加。
Pediatr Infect Dis J. 2007 Dec;26(12):1122-7. doi: 10.1097/INF.0b013e31814536e0.
4
Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus.细微的基因变化增强了耐甲氧西林金黄色葡萄球菌和甲氧西林敏感金黄色葡萄球菌的毒力。
BMC Microbiol. 2007 Nov 6;7:99. doi: 10.1186/1471-2180-7-99.
5
Evolution and pathogenesis of Staphylococcus aureus: lessons learned from genotyping and comparative genomics.金黄色葡萄球菌的进化与发病机制：从基因分型和比较基因组学中学到的经验教训。
FEMS Microbiol Rev. 2008 Jan;32(1):23-37. doi: 10.1111/j.1574-6976.2007.00086.x. Epub 2007 Nov 5.
6
Epidemiologic distribution of the arginine catabolic mobile element among selected methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates.精氨酸分解代谢移动元件在部分耐甲氧西林和甲氧西林敏感金黄色葡萄球菌分离株中的流行病学分布
J Clin Microbiol. 2007 Jun;45(6):1981-4. doi: 10.1128/JCM.00273-07. Epub 2007 Apr 4.
7
Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus.社区获得性耐甲氧西林金黄色葡萄球菌流行克隆USA300的全基因组序列
Lancet. 2006 Mar 4;367(9512):731-9. doi: 10.1016/S0140-6736(06)68231-7.
8
Partial excision of the chromosomal cassette containing the methicillin resistance determinant results in methicillin-susceptible Staphylococcus aureus.切除含有耐甲氧西林决定簇的染色体盒的一部分会产生对甲氧西林敏感的金黄色葡萄球菌。
J Clin Microbiol. 2005 Aug;43(8):4191-3. doi: 10.1128/JCM.43.8.4191-4193.2005.
9
A clone of methicillin-resistant Staphylococcus aureus among professional football players.职业足球运动员中耐甲氧西林金黄色葡萄球菌的一个克隆株。
N Engl J Med. 2005 Feb 3;352(5):468-75. doi: 10.1056/NEJMoa042859.
10
A high-morbidity outbreak of methicillin-resistant Staphylococcus aureus among players on a college football team, facilitated by cosmetic body shaving and turf burns.一支大学橄榄球队的队员中发生了耐甲氧西林金黄色葡萄球菌高发病率的疫情，这是由身体美容剃须和草坪擦伤促成的。
Clin Infect Dis. 2004 Nov 15;39(10):1446-53. doi: 10.1086/425313. Epub 2004 Oct 26.
Zotero 插件