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捷克共和国首例婴儿由产化脓性链球菌杀白细胞素的金黄色葡萄球菌引起的致命性肺炎。

The first case of fatal pneumonia caused by Panton-Valentine leukocidin-producing Staphylococcus aureus in an infant in the Czech Republic.

机构信息

1st Department of Infectious Diseases, Bulovka Hospital, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

出版信息

Folia Microbiol (Praha). 2013 May;58(3):225-8. doi: 10.1007/s12223-012-0200-z. Epub 2012 Oct 17.

Abstract

Panton-Valentine leukocidin-producing strains of Staphylococcus aureus can cause severe skin and soft tissue infections and necrotizing pneumonia with a high mortality rate. This is a report on the first case of fatal pneumonia with mediastinitis in an infant in the Czech Republic. The causative agent was a methicillin-susceptible S. aureus strain with pronounced production of the PVL toxin and hyperproduction of enterotoxin A.

摘要

金黄色葡萄球菌产 Panton-Valentine 白细胞毒素菌株可引起严重的皮肤和软组织感染和坏死性肺炎,死亡率很高。这是捷克共和国首例致命性肺炎合并纵隔炎婴儿病例报告。病原体是一株耐甲氧西林的金黄色葡萄球菌,该菌株明显产生 PVL 毒素和肠毒素 A 的超量产生。

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