Kotani Shinsuke, Hattori Koji, Kato Yasuyuki, Shibata Toshihiko
Department of Cardiovascular Surgery, Osaka City General Hospital, Miyakojima, Osaka, Japan.
Interact Cardiovasc Thorac Surg. 2010 Mar;10(3):486-8. doi: 10.1510/icvts.2009.220707. Epub 2009 Dec 10.
We report an uncommon case of thrombogenesis in the distal aortic arch after apicoaortic conduit (AAC) for severe aortic stenosis (AS). A 71-year-old woman underwent AAC with a bioprosthetic valve for severe AS because of heavy calcification of the ascending aorta. Although anticoagulant therapy with warfarin was performed, a postoperative computed tomographic (CT) scan revealed a thrombus in the distal aortic arch. Cine magnetic resonance imaging (MRI) revealed stagnation of the blood flow at that site. Administration of warfarin was continued. A follow-up CT-scan showed a marked reduction of the thrombus at six months after the surgery. A follow-up MRI revealed that the antegrade flow through the native aortic valve was decreased at one year after the surgery. We suggest that thrombogenesis may occur after AAC because of stagnation of the blood flow and that the distribution of the blood flow may change during the follow-up period. Therefore, we recommend that postoperative anticoagulant therapy should be initiated immediately, even when a bioprosthetic valve is used.
我们报告了一例罕见的病例,在因严重主动脉瓣狭窄(AS)行主动脉顶端导管(AAC)术后,远端主动脉弓发生血栓形成。一名71岁女性因升主动脉重度钙化,接受了AAC并植入生物瓣膜治疗严重AS。尽管使用华法林进行了抗凝治疗,但术后计算机断层扫描(CT)显示远端主动脉弓有血栓形成。电影磁共振成像(MRI)显示该部位血流停滞。继续使用华法林治疗。术后6个月的随访CT扫描显示血栓明显缩小。术后1年的随访MRI显示,通过天然主动脉瓣的正向血流减少。我们认为,AAC术后可能因血流停滞而发生血栓形成,且随访期间血流分布可能发生变化。因此,我们建议即使使用生物瓣膜,术后也应立即开始抗凝治疗。