Department of Ophthalmology, Antwerp University Hospital, Faculty of Medicine, Antwerp University, Belgium.
Invest Ophthalmol Vis Sci. 2010 May;51(5):2800-4. doi: 10.1167/iovs.09-4679. Epub 2009 Dec 10.
To quantify the changes in retinal straylight that occur after laser-assisted subepithelial keratectomy (LASEK).
This prospective study included 86 eyes of 49 patients who were scheduled for LASEK surgery. Patients were divided into groups based on their preoperative contact lens wear habits: rigid lenses (RCL), soft lenses (SCL), spectacles after a period of contact lenses (SaC), and spectacles only (Specs). Retinal straylight was tested before surgery and 6 months after surgery with the compensation comparison method. Straylight was also compared to a normal reference database. The difference with the average straylight increase with age, called base- and age-corrected (BAC) straylight, was also studied.
Before surgery, BAC straylight was found to be strongly elevated, with a value of 0.15 +/- 0.14 log units. After LASEK, this decreased to 0.00 +/- 0.14 log units. The reduction was significant (paired t-test, P << 0.01) and correlated with preoperative BAC straylight levels (r(2) = 0.332; P << 0.01). There was no correlation between the straylight change and the spherical equivalent of the laser refractive correction (r(2) = 0.042; P = 0.059). Preoperative wear of soft contact lenses increased the BAC straylight by approximately 0.06 log units, with respect to the spectacles groups (P < 0.05, unpaired t-test), but after surgery, this difference was no longer found (P > 0.05).
Higher than normal preoperative BAC straylight was found to normalize after LASEK refractive surgery. Wearing soft contact lenses causes an additional increase in preoperative BAC straylight that is eliminated after LASEK.
定量分析激光辅助上皮下角膜切除术(LASEK)后视网膜散射光的变化。
本前瞻性研究纳入了 49 名患者的 86 只眼,这些患者均计划行 LASEK 手术。患者根据术前接触镜佩戴习惯分为以下几组:硬性隐形眼镜(RCL)组、软性隐形眼镜(SCL)组、停戴接触镜一段时间后戴框架镜(SaC)组和仅戴框架镜(Specs)组。分别于术前和术后 6 个月采用补偿对比法检测视网膜散射光。并与正常参考数据库进行比较。还研究了与年龄相关的平均散射光增加量的差异,称为基底和年龄校正(BAC)散射光。
术前 BAC 散射光值明显升高,为 0.15±0.14log 单位。LASEK 术后,该值降至 0.00±0.14log 单位。差异具有统计学意义(配对 t 检验,P<<0.01),且与术前 BAC 散射光水平相关(r²=0.332;P<<0.01)。散射光变化与激光屈光矫正的等效球镜无相关性(r²=0.042;P=0.059)。与框架镜组相比,术前软性接触镜佩戴者的 BAC 散射光增加约 0.06log 单位(P<0.05,非配对 t 检验),但术后这种差异不再存在(P>0.05)。
LASEK 屈光手术后,高于正常的术前 BAC 散射光恢复正常。软性接触镜的佩戴会导致术前 BAC 散射光的额外增加,这种增加在 LASEK 术后会消除。