细胞外 PAS 样结构域常见于信号转导蛋白中。
Extracytoplasmic PAS-like domains are common in signal transduction proteins.
机构信息
Biosciences Division, Argonne National Laboratory, Argonne, Illinois 60439, USA.
出版信息
J Bacteriol. 2010 Feb;192(4):1156-9. doi: 10.1128/JB.01508-09. Epub 2009 Dec 11.
Abstract
We present the crystal structure of the extracytoplasmic domain of the Bacillus subtilis PhoR sensor histidine kinase, part of a two-component system involved in adaptation to low environmental phosphate concentrations. In addition to the PhoR structure, we predict that the majority of the extracytoplasmic domains of B. subtilis sensor kinases will adopt a fold similar to the ubiquitous PAS domain.
摘要
我们展示了枯草芽孢杆菌 PhoR 感应组氨酸激酶胞外结构域的晶体结构，该激酶是参与适应低环境磷酸盐浓度的双组分系统的一部分。除了 PhoR 结构外，我们预测枯草芽孢杆菌传感器激酶的大多数胞外结构域将采用类似于普遍存在的 PAS 结构域的折叠。
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