Thomas Nick
GE Healthcare, Whitchurch, Cardiff, United Kingdom.
J Biomol Screen. 2010 Jan;15(1):1-9. doi: 10.1177/1087057109353790. Epub 2009 Dec 11.
In the past decade, high-content screening has become a highly developed approach to obtaining richly descriptive quantitative phenotypic data using automated microscopy. From early use in drug screening, the technique has evolved to embrace a diverse range of applications in both academic and industrial sectors and is now widely recognized as providing an efficient and effective approach to large-scale programs investigating cell biology in situ and in context.
在过去十年中，高内涵筛选已成为一种高度发达的方法，可利用自动显微镜获取丰富的描述性定量表型数据。从早期在药物筛选中的应用开始，该技术已发展到涵盖学术和工业领域的各种应用，现在被广泛认为是为大规模原位和背景下研究细胞生物学的项目提供了一种高效且有效的方法。
