肾脏成纤维细胞的起源与肾脏疾病的进展。
The origin of renal fibroblasts and progression of kidney disease.
机构信息
Department of Histopathology, Imperial College, Du Cane Rd, London W12 0NN, UK.
出版信息
Am J Pathol. 2010 Jan;176(1):22-4. doi: 10.2353/ajpath.2010.090898. Epub 2009 Dec 11.
Abstract
The Commentary highlights the article by Humphreys et al, “Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis” discussing hypothesis of renal progression.
摘要
述评强调了 Humphreys 等人的文章，“命运追踪揭示了肾脏纤维化中肌成纤维细胞的周细胞而非上皮细胞起源”，讨论了肾脏进展的假说。
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本文引用的文献
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2
Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy.上皮-间质转化作为糖尿病肾病中足细胞耗竭的一种潜在解释。
Am J Kidney Dis. 2009 Oct;54(4):653-64. doi: 10.1053/j.ajkd.2009.05.009. Epub 2009 Jul 17.
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Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney.周细胞和血管周围成纤维细胞是肾梗阻性纤维化中产生胶原蛋白细胞的主要来源。
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