Dagnelie P C, van Staveren W A, van den Berg H
Department of Human Nutrition, Wageningen Agricultural University, The Netherlands.
Am J Clin Nutr. 1991 Mar;53(3):695-7. doi: 10.1093/ajcn/53.3.695.
The effect of algae (nori and spirulina) and fermented plant foods on the hematological status of vitamin B-12-deficient children was evaluated. Although rising plasma vitamin B-12 concentrations in children consuming only plant foods (0.1-2.7 micrograms vitamin B-12/d) indicated that the vitamin B-12 was absorbed, elevated baseline values of mean corpuscular volume (MCV) further deteriorated. In contrast, MCV improved in children receiving fish containing 0.15-0.5 microgram vitamin B-12/d or a vitamin B-12 supplement. Further studies on the specificity of current vitamin B-12 assays are warranted. It seems unjustified to advocate algae and other plant foods as a safe source of vitamin B-12 because its bioavailability is questionable.
评估了藻类（紫菜和螺旋藻）及发酵植物性食物对维生素B-12缺乏儿童血液学状况的影响。尽管仅食用植物性食物（每日摄入0.1 - 2.7微克维生素B-12）的儿童血浆维生素B-12浓度升高表明维生素B-12被吸收，但平均红细胞体积（MCV）的基线值升高进一步恶化。相比之下，每日摄入含0.15 - 0.5微克维生素B-12的鱼类或补充维生素B-12的儿童MCV有所改善。有必要对当前维生素B-12检测方法的特异性进行进一步研究。由于其生物利用度存疑，提倡将藻类和其他植物性食物作为维生素B-12的安全来源似乎不合理。
