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可食用藻类中维生素B12化合物的表征及生物利用度

Characterization and bioavailability of vitamin B12-compounds from edible algae.

作者信息

Watanabe Fumio, Takenaka Shigeo, Kittaka-Katsura Hiromi, Ebara Shuhei, Miyamoto Emi

机构信息

Department of Health Science, Kochi Women's University, Kochi 780-8515, Japan.

出版信息

J Nutr Sci Vitaminol (Tokyo). 2002 Oct;48(5):325-31. doi: 10.3177/jnsv.48.325.

DOI:10.3177/jnsv.48.325
PMID:12656203
Abstract

Substantial amounts of vitamin B12 were found in some edible algae (green and purple lavers) and algal health food (chlorella and spirulina tablets) using the Lactobacillus delbrueckii subsp. lactis ATCC7830 microbiological assay method. Corrinoid-compounds were purified and characterized from these algae to clarify the chemical properties and bioavailability of the algal vitamin B12. True vitamin B12 is the predominate cobamide of green and purple lavers and chlorella tablets. Feeding the purple laver to vitamin B12-deficient rats significantly improved the vitamin B12 status. The results suggest that algal vitamin B12 is a bioavailable source for mammals. Pseudovitamin B12 (an inactive corrinoid) predominated in the spirulina tablets, which are not suitable for use as a vitamin B12 source, especially for vegetarians. algal health food, bioavailability, cobalamin, edible algae, vitamin B12

摘要

使用德氏乳杆菌乳酸亚种ATCC7830微生物检测方法,在一些可食用藻类(绿紫菜和紫紫菜)以及藻类保健食品(小球藻片和螺旋藻片)中发现了大量的维生素B12。从这些藻类中纯化并鉴定了类咕啉化合物,以阐明藻类维生素B12的化学性质和生物利用度。真正的维生素B12是绿紫菜、紫紫菜和小球藻片中的主要钴胺素。给维生素B12缺乏的大鼠喂食紫紫菜可显著改善其维生素B12状况。结果表明,藻类维生素B12是哺乳动物可利用的维生素来源。伪维生素B12(一种无活性的类咕啉)在螺旋藻片中占主导地位,螺旋藻片不适合用作维生素B12来源,尤其是对素食者而言。藻类保健食品、生物利用度、钴胺素、可食用藻类、维生素B12

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