Firestone Institute for Respiratory Health, St. Joseph's Hospital and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Proc Am Thorac Soc. 2009 Dec;6(8):720-3. doi: 10.1513/pats.200907-059DP.
Achieving asthma control is the focus of asthma management. Inhaled corticosteroids are the most effective treatment for asthma in children and adults, with no evidence that the magnitude of benefit differs between adults and school-aged children. Leukotriene inhibitors are more widely used in children than in adults. This may be because provoking stimuli, such as environmental allergens and frequent exercise, are more important asthma triggers in children or because parental concerns about the side effects of treatment with ICS. Inhaled corticosteroid/long-acting inhaled beta(2)-agonist combinations may not be as effective in children as in they are adults in improving asthma control and reducing asthma exacerbations.
实现哮喘控制是哮喘管理的重点。吸入皮质类固醇是儿童和成人哮喘最有效的治疗方法，没有证据表明其疗效在成人和学龄儿童之间存在差异。白三烯抑制剂在儿童中的应用比在成人中更为广泛。这可能是因为在儿童中，诱发因素（如环境过敏原和频繁运动）更为重要，或者是因为父母对 ICS 治疗的副作用存在担忧。吸入皮质类固醇/长效吸入β2-激动剂联合治疗在改善哮喘控制和减少哮喘恶化方面，在儿童中的效果可能不如在成人中。
