Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, 610 Walnut Street, Madison, WI 53726, USA.
Am J Epidemiol. 2010 Jan 15;171(2):260-6. doi: 10.1093/aje/kwp370. Epub 2009 Dec 15.
There were significant changes in health and lifestyle throughout the 20th century which may have changed temporal patterns of hearing impairment in adults. In this study, the authors aimed to assess the effect of birth cohort on the prevalence of hearing impairment in an adult population aged 45-94 years, using data collected between 1993 and 2008 from 3 cycles of the Epidemiology of Hearing Loss Study (n = 3,753; ages 48-92 years at baseline) and a sample of participants from the Beaver Dam Offspring Study (n = 2,173; ages > or =45 years). Hearing impairment was defined as a pure-tone average of thresholds at 0.5, 1, 2, and 4 kHz greater than 25-dB HL [hearing level]. Descriptive analysis, generalized additive models, and alternating logistic regression models were used to examine the birth cohort effect. Controlling for age, with every 5-year increase in birth year, the odds of having hearing impairment were 13% lower in men (odds ratio = 0.87, 95% confidence interval: 0.83, 0.92) and 6% lower in women (odds ratio = 0.94, 95% confidence interval: 0.89, 0.98). These results suggest that 1) older adults may be retaining good hearing longer than previous generations and 2) modifiable factors contribute to hearing impairment in adults.
20 世纪,人们的健康和生活方式发生了重大变化,这可能改变了成年人听力障碍的时间模式。在这项研究中,作者旨在使用 1993 年至 2008 年间收集的 3 个听力损失流行病学研究周期的数据(n = 3753;基线时年龄为 48-92 岁)和 Beaver Dam 后代研究(n = 2173;年龄 > = 45 岁)中参与者的样本,评估出生队列对 45-94 岁成年人听力障碍患病率的影响。听力障碍定义为 0.5、1、2 和 4 kHz 纯音平均阈值大于 25-dB HL [听力水平]。使用描述性分析、广义加性模型和交替逻辑回归模型来检查出生队列效应。在控制年龄的情况下,与出生年份每增加 5 年相比,男性听力障碍的几率降低 13%(比值比 = 0.87,95%置信区间:0.83,0.92),女性降低 6%(比值比 = 0.94,95%置信区间:0.89,0.98)。这些结果表明:1)老年人可能比前几代人更能长时间保持良好的听力;2)可改变的因素导致成年人听力障碍。