CEA, I(2)BM, Service Hospitalier Frédéric Joliot, LIME, INSERM U803, 91400 Orsay, France.
J Nucl Med. 2010 Jan;51(1):1-4. doi: 10.2967/jnumed.109.065680. Epub 2009 Dec 15.
Inflammatory responses are closely associated with many neurologic disorders and influence their outcome. In vivo imaging can document events accompanying neuroinflammation, such as changes in blood flow, vascular permeability, tightness of the blood-to-brain barrier, local metabolic activity, and expression of specific molecular targets. Here, we briefly review current methods for imaging neuroinflammation, with special emphasis on nuclear imaging techniques.
炎症反应与许多神经疾病密切相关，并影响其结果。体内成像可以记录伴随神经炎症的事件，如血流变化、血管通透性、血脑屏障的紧密性、局部代谢活性以及特定分子靶标的表达。在这里，我们简要回顾了目前用于成像神经炎症的方法，特别强调了核成像技术。
