植物防御素：防御、发育与应用。
Plant defensins: defense, development and application.
机构信息
Julius-von-Sachs-Institut fuer Biowissenschaften, Pharmazeutische Biologie, Biozentrum, Universitaet Wuerzburg, Wuerzburg, Germany.
出版信息
Plant Signal Behav. 2009 Nov;4(11):1010-2. doi: 10.4161/psb.4.11.9755. Epub 2009 Nov 7.
Abstract
Plant defensins are small, highly stable, cysteine-rich peptides that constitute a part of the innate immune system primarily directed against fungal pathogens. Biological activities reported for plant defensins include antifungal activity, antibacterial activity, proteinase inhibitory activity and insect amylase inhibitory activity. Plant defensins have been shown to inhibit infectious diseases of humans and to induce apoptosis in a human pathogen. Transgenic plants overexpressing defensins are strongly resistant to fungal pathogens. Based on recent studies, some plant defensins are not merely toxic to microbes but also have roles in regulating plant growth and development.
摘要
植物防御素是小而稳定的富含半胱氨酸的肽，是先天免疫系统的一部分，主要针对真菌病原体。已报道植物防御素有抗真菌活性、抗菌活性、蛋白酶抑制活性和昆虫淀粉酶抑制活性。植物防御素已被证明可抑制人类传染病，并诱导人类病原体细胞凋亡。过表达防御素的转基因植物对真菌病原体具有很强的抗性。基于最近的研究，一些植物防御素不仅对微生物有毒，而且在调节植物生长和发育中也具有作用。
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