Thevissen Karin, Ferket Kathelijne K A, François Isabelle E J A, Cammue Bruno P A
Centre of Microbial and Plant Genetics (CMPG), Katholieke Universiteit Leuven, Kasteelpark Arenberg 20, B-3001 Heverlee, Belgium.
Peptides. 2003 Nov;24(11):1705-12. doi: 10.1016/j.peptides.2003.09.014.
Plant defensins are small, basic, cysteine-rich peptides that are generally active against a broad spectrum of fungal and yeast species at micromolar concentrations. Some of these defensins interact with fungal-specific lipid components in the plasmamembrane. Structural differences of these membrane components between fungal and plant cells probably account for the selective activity of plant defensins against fungal pathogens and their nonphytotoxic properties. This review will focus on different classes of complex lipids in fungal membranes and on the selective interaction of plant defensins with these complex lipids.
植物防御素是一类小的、碱性的、富含半胱氨酸的肽，通常在微摩尔浓度下对多种真菌和酵母具有活性。其中一些防御素与质膜中真菌特异性脂质成分相互作用。真菌和植物细胞之间这些膜成分的结构差异可能解释了植物防御素对真菌病原体的选择性活性及其非植物毒性特性。本综述将聚焦于真菌膜中不同类别的复合脂质，以及植物防御素与这些复合脂质的选择性相互作用。
