MMWR Morb Mortal Wkly Rep. 2009 Dec 11;58(48):1341-4.
Indigenous populations from Australia, Canada, and New Zealand have been found to have a three to eight times higher rate of hospitalization and death associated with infection with the 2009 pandemic influenza A (H1N1) virus. In October, two U.S. states (Arizona and New Mexico) observed a disproportionate number of deaths related to H1N1 among American Indian/Alaska Natives (AI/ANs). These observations, plus incomplete reporting of race/ethnicity at the national level, led to formation of a multidisciplinary workgroup comprised of representatives from 12 state health departments, the Council of State and Territorial Epidemiologists, tribal epidemiology centers, the Indian Health Service, and CDC. The workgroup assessed the burden of H1N1 influenza deaths in the AI/AN population by compiling surveillance data from the states and comparing death rates. The results indicated that, during April 15-November 13, AI/ANs in the 12 participating states had an H1N1 mortality rate four times higher than persons in all other racial/ethnic populations combined. Reasons for this disparity in death rates are unknown and need further investigation; however, they might include a high prevalence of chronic health conditions (e.g., diabetes and asthma) among AI/ANs that predisposes them to influenza complications, poverty (e.g., poor living conditions), and delayed access to care. Efforts are needed to increase awareness among AI/ANs and their health-care providers of the potential severity of influenza and current recommendations regarding the timely use of antiviral medications. Efforts to promote the use of 2009 H1N1 influenza monovalent vaccine in AI/AN populations should be expanded.
澳大利亚、加拿大和新西兰的原住民感染2009年甲型H1N1大流行性流感病毒后,住院率和死亡率高出三到八倍。10月,美国两个州(亚利桑那州和新墨西哥州)发现,美国印第安人/阿拉斯加原住民(AI/ANs)中与H1N1相关的死亡人数过多。这些观察结果,加上国家层面种族/族裔报告不完整,促使成立了一个多学科工作组,成员包括来自12个州卫生部门、州和地区流行病学家理事会、部落流行病学中心、印第安卫生服务机构和疾病预防控制中心的代表。该工作组通过汇总各州的监测数据并比较死亡率,评估了AI/AN人群中H1N1流感死亡的负担。结果表明,在4月15日至11月13日期间,12个参与州的AI/ANs的H1N1死亡率比所有其他种族/族裔人群的总和高出四倍。死亡率存在这种差异的原因尚不清楚,需要进一步调查;然而,这些原因可能包括AI/ANs中慢性健康状况(如糖尿病和哮喘)的高患病率,这使他们易患流感并发症、贫困(如生活条件差)以及获得医疗服务的机会延迟。需要做出努力,提高AI/ANs及其医疗服务提供者对流感潜在严重性以及当前关于及时使用抗病毒药物建议的认识。应扩大在AI/AN人群中推广使用2009年H1N1流感单价疫苗的努力。