Ludwig Kirk A
Duke University Medical Center, Durham, NC 27710, USA.
Clin Colon Rectal Surg. 2007 Aug;20(3):203-12. doi: 10.1055/s-2007-984864.
Although there is still a place for abdominoperineal resection in the treatment of rectal cancer, the state of the art is sphincter-preserving resection. Even for the lowest of rectal cancers, using a combination of neoadjuvant chemo/radiation, total mesorectal excision, and intersphincteric proctectomy and colonic J-pouch to anal anastomosis, sphincter preservation can be achieved for most patients. The key concept in pushing sphincter preservation forward has been the realization that the deep, circumferential, or lateral margin is all-important. Unless the rectal tumor involves the external sphincter muscle, there is no oncologic need to remove it, and following resection of the tumor, gastrointestinal tract continuity can be restored.
尽管腹会阴联合切除术在直肠癌治疗中仍有一席之地,但目前的先进技术是保留括约肌的切除术。即使是低位直肠癌,通过新辅助化疗/放疗、全直肠系膜切除术、括约肌间直肠切除术以及结肠J形贮袋肛管吻合术相结合,大多数患者也能够实现括约肌保留。推动括约肌保留技术发展的关键理念是认识到深部、环周或侧切缘至关重要。除非直肠肿瘤累及外括约肌,否则从肿瘤学角度无需切除它,并且在肿瘤切除后,可恢复胃肠道的连续性。