Hammond Kerry, Margolin David A
Department of Colon and Rectal Surgery, Ochsner Clinic Foundation, New Orleans, LA 70121, USA.
Clin Colon Rectal Surg. 2007 Aug;20(3):249-54. doi: 10.1055/s-2007-984869.
Postoperative surveillance for recurrent and/or metachronous disease is an important component of the treatment of patients with colorectal cancer. The optimal schedule of follow-up investigations remains controversial. Several randomized trials have suggested a moderate improvement in 5-year survival and earlier detection of cancer recurrence with the implementation of intensive surveillance protocols. Whether these protocols are cost-effective has yet to be determined. Current guidelines from the American Society of Colon and Rectal Surgeons recommend periodic patient follow-up with office visits, carcinoembryonic antigen (CEA) measurement, and endoscopy following potentially curative resection of colorectal cancer.
对复发性和/或异时性疾病进行术后监测是结直肠癌患者治疗的重要组成部分。随访检查的最佳时间表仍存在争议。几项随机试验表明，实施强化监测方案可适度提高5年生存率，并能更早发现癌症复发。这些方案是否具有成本效益尚未确定。美国结直肠外科医师协会的现行指南建议，在结直肠癌进行潜在根治性切除术后，对患者进行定期随访，包括门诊就诊、癌胚抗原（CEA）检测和内镜检查。
