基于功能化富勒烯纳米材料的生物医学应用。
Biomedical applications of functionalized fullerene-based nanomaterials.
机构信息
Center for Translational Injury Research, The University of Texas Health Science Center, Houston, 77030, USA.
出版信息
Int J Nanomedicine. 2009;4:261-75.
Since their discovery in 1985, fullerenes have been investigated extensively due to their unique physical and chemical properties. In recent years, studies on functionalized fullerenes for various applications in the field of biomedical sciences have seen a significant increase. The ultimate goal is towards employing these functionalized fullerenes in the diagnosis and therapy of human diseases. Functionalized fullerenes are one of the many different classes of compounds that are currently being investigated in the rapidly emerging field of nanomedicine. In this review, the focus is on the three categories of drug delivery, reactive oxygen species quenching, and targeted imaging for which functionalized fullerenes have been studied in depth. In addition, an exhaustive list of the different classes of functionalized fullerenes along with their applications is provided. We will also discuss and summarize the unique approaches, mechanisms, advantages, and the aspect of toxicity behind utilizing functionalized fullerenes for biomedical applications.
自 1985 年被发现以来，由于其独特的物理和化学性质，富勒烯受到了广泛的研究。近年来，在生物医学科学领域的各种应用中，对功能化富勒烯的研究有了显著的增加。最终目标是将这些功能化富勒烯应用于人类疾病的诊断和治疗。功能化富勒烯是纳米医学这一快速发展领域中正在研究的众多不同化合物类别之一。在这篇综述中，重点关注了功能化富勒烯在药物输送、活性氧物种猝灭和靶向成像这三个类别中的深入研究。此外，还提供了功能化富勒烯及其应用的不同类别列表。我们还将讨论并总结利用功能化富勒烯进行生物医学应用的独特方法、机制、优势和毒性方面。
Zotero 插件