LaRocque Justin, Bharali Dhruba J, Mousa Shaker A
Albany College of Pharmacy and Health Sciences, Rensselaer, NY 12144, USA.
Mol Biotechnol. 2009 Jul;42(3):358-66. doi: 10.1007/s12033-009-9161-0. Epub 2009 Mar 17.
Nanotechnology is a field which has been at the forefront of research over the past two decades. The full potential of nanotechnology has yet to be fully realized. One subset of nanotechnology that has emerged is nanomedicine, which has been able to exploit the unique properties of nano-sized particles for therapeutics. Nanomedicine has the potential to increase the specific treatment of cancer cells while leaving healthy cells intact through the use of novel nanoparticles to seek and treat cancer in the human body. However, there are undoubtedly toxicities, which have not yet been fully elucidated. Various nano-carriers such as nanoshells, nanocrystals, nanopolymers, quantum dots, and dendrimers, and their role in early cancer detection and treatment have been discussed in this article.
纳米技术是过去二十年来一直处于研究前沿的领域。纳米技术的全部潜力尚未得到充分发挥。已出现的纳米技术的一个分支是纳米医学,它能够利用纳米级粒子的独特性质进行治疗。纳米医学有潜力通过使用新型纳米粒子在人体内寻找和治疗癌症,从而在不损害健康细胞的情况下增强对癌细胞的特异性治疗。然而,毫无疑问存在毒性,但其尚未得到充分阐明。本文讨论了各种纳米载体,如纳米壳、纳米晶体、纳米聚合物、量子点和树枝状大分子,以及它们在早期癌症检测和治疗中的作用。