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炎症性肠病行直肠结肠切除术后的回肠储袋修复手术:既往经验与未来方向。

Restorative pouch surgery following proctocolectomy for inflammatory bowel disease: past experience and future direction.

作者信息

Cohen David, Silvestri Caitlin, Schwartzberg David M

机构信息

Department of Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.

Inflammatory Bowel Disease Center, Division of Colorectal Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.

出版信息

Transl Gastroenterol Hepatol. 2023 Jul 25;8:27. doi: 10.21037/tgh-23-28. eCollection 2023.

Abstract

Major advancements in surgery for patients suffering proctocolitis from ulcerative colitis (UC) or selected patients with Crohn's disease (CD) have emerged in a relatively short time. Historically, patients underwent a proctocolectomy with end ileostomy, however, a restorative proctocolectomy with an ileal pouch-anal anastomosis (IPAA) was introduced in the late 1970s in the United Kingdom and gave patients the opportunity to avoid a permanent stoma. Initially designed as a hand-sewn "S" shaped pouch, with the invention of the linear stapler, a "J" shaped pouch was described in Japan, and subsequent advances in the United States largely contributed to the pelvic pouch's evolution to the standard of care in the management of patients with inflammatory bowel disease (IBD). The procedure was then divided into different stages depending on the medical condition of the patient and minimally invasive techniques (laparoscopic & robotic surgery) have continued to advance the success of the operation. Unfortunately, pouch complications occur, and seem to be occurring at an increasing frequency with the adoption of minimally invasive surgery. The field of reoperative pouch surgery has emerged to offer patients the opportunity to restore their quality of life (QOL) without the need for a permanent ostomy. Many patients with signs of pouch failure such as pouchitis, fistulae, pain and obstruction are diagnosed with Crohn's of the pouch, but many have mechanical complications that can be corrected with surgery, rather than offering pouch excision with a permanent ostomy (continent or traditional). Patients with Crohn's may be offered an IPAA but they will not have success if they, like patients with UC, have mechanical complications leading to their pouch failure. Patients who undergo reoperative pouch surgery do well with an acceptable QOL.

摘要

在相对较短的时间内,针对溃疡性结肠炎(UC)所致直肠结肠炎患者或部分克罗恩病(CD)患者的外科手术取得了重大进展。从历史上看,患者需接受直肠结肠切除术并进行末端回肠造口术,然而,20世纪70年代末英国引入了带回肠贮袋肛管吻合术(IPAA)的保留性直肠结肠切除术,使患者有机会避免永久性造口。最初设计为手工缝合的“S”形贮袋,随着线性吻合器的发明,日本描述了“J”形贮袋,美国随后的进展在很大程度上推动了盆腔贮袋在炎症性肠病(IBD)患者管理中成为标准治疗方法。然后根据患者的病情将该手术分为不同阶段,微创技术(腹腔镜和机器人手术)不断提高手术成功率。不幸的是,贮袋并发症时有发生,而且随着微创手术的采用,其发生率似乎在增加。再次手术贮袋手术领域应运而生,为患者提供了无需永久性造口即可恢复生活质量(QOL)的机会。许多有贮袋失败迹象(如贮袋炎、瘘管、疼痛和梗阻)的患者被诊断为贮袋型克罗恩病,但许多患者有可通过手术纠正的机械性并发症,而不是进行永久性造口(可控性或传统性)的贮袋切除术。克罗恩病患者可能会接受IPAA手术,但如果他们像UC患者一样有导致贮袋失败的机械性并发症,手术就不会成功。接受再次手术贮袋手术的患者生活质量良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5f9/10432232/3181e0e1f8d5/tgh-08-23-28-f1.jpg

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