Mills Steven, Stamos Michael J
Division of Colon and Rectal Surgery, Department of Surgery, University of California, Irvine, Orange, CA 92868, USA.
Clin Colon Rectal Surg. 2007 Nov;20(4):309-13. doi: 10.1055/s-2007-991030.
Crohn's disease is an inflammatory disease of the gastrointestinal (GI) tract of uncertain etiology. It can affect any portion of the GI tract, involving the colon in approximately 60% of cases. Diagnosis can be unclear, but suspicion can be raised based upon clinical, endoscopic, and pathologic findings. Initial management is often medical, with surgery reserved for patients with colonic complications of Crohn's disease, such as hemorrhage, fulminant colitis, abscess or fistula, stricture, and malignant transformation. The operative choice and conduct depends upon the clinical presentation and intraoperative findings. The extent of resection is controversial, but segmental resection is appropriate in selected cases.
克罗恩病是一种病因不明的胃肠道炎症性疾病。它可累及胃肠道的任何部位,约60%的病例累及结肠。诊断可能不明确,但可根据临床、内镜和病理检查结果提高怀疑指数。初始治疗通常为药物治疗,手术仅适用于患有克罗恩病结肠并发症的患者,如出血、暴发性结肠炎、脓肿或瘘管、狭窄以及恶变。手术方式的选择和实施取决于临床表现和术中所见。切除范围存在争议,但在某些特定病例中节段性切除是合适的。