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腹腔镜直肠癌手术:随机试验的必要性。

Laparoscopy for rectal cancer: the need for randomized trials.

作者信息

Read Thomas E, Marcello Peter W

机构信息

Division of Colon and Rectal Surgery, Western Pennsylvania Hospital, Temple University School of Medicine, Pittsburgh, PA 15224, USA.

出版信息

Clin Colon Rectal Surg. 2006 Feb;19(1):13-8. doi: 10.1055/s-2006-939526.

Abstract

The adoption of laparoscopic proctectomy for rectal cancer has been relatively slow, primarily because of the technical difficulty of the procedure. The wide surgeon-to-surgeon variability in disease-free survival and local pelvic recurrence noted after open proctectomy is probably due to differences in surgical technique, and these differences are likely to be magnified when the additional challenge of laparoscopy is added to the procedure. At present, oncologic and functional outcomes data are limited. Although the adoption of laparoscopic techniques to perform curative proctectomy is likely to expand as technical challenges are overcome and experience and training improve, the results of prospective multicenter trials are necessary to ensure that the procedures provide an oncologic and functional outcome equivalent to that of conventional surgery.

摘要

腹腔镜直肠癌切除术的应用相对缓慢,主要是因为该手术技术难度较大。开腹直肠癌切除术后无病生存率和局部盆腔复发率在外科医生之间差异很大,这可能是由于手术技术的不同,而当手术增加了腹腔镜这一额外挑战时,这些差异可能会被放大。目前,肿瘤学和功能结局数据有限。尽管随着技术挑战被克服以及经验和培训的改进,采用腹腔镜技术进行根治性直肠切除术的情况可能会增加,但仍需要前瞻性多中心试验的结果来确保这些手术能提供与传统手术相当的肿瘤学和功能结局。

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